By the same authors

From the same journal

Methodologies for quantitative systems pharmacology (QSP) models: Design and estimation

Research output: Contribution to journalReview articlepeer-review


  • B. Ribba
  • H. P. Grimm
  • B. Agoram
  • M. R. Davies
  • K. Gadkar
  • S. Niederer
  • N. Van Riel
  • J. Timmis
  • P. H. Van Der Graaf


Publication details

JournalCPT Pharmacometrics & Systems Pharmacology
DateAccepted/In press - 9 May 2017
DateE-pub ahead of print - 11 Jul 2017
DatePublished (current) - 1 Aug 2017
Issue number8
Number of pages3
Pages (from-to)496-498
Early online date11/07/17
Original languageEnglish


With the increased interest in the application of quantitative systems pharmacology (QSP) models within medicine research and development, there is an increasing need to formalize model development and verification aspects. In February 2016, a workshop was held at Roche Pharma Research and Early Development to focus discussions on two critical methodological aspects of QSP model development: optimal structural granularity and parameter estimation. We here report in a perspective article a summary of presentations and discussions.

Bibliographical note

© 2017 The Authors

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