By the same authors

From the same journal

From the same journal

Microbial mutualism at a distance: The role of geometry in diffusive exchanges

Research output: Contribution to journalArticlepeer-review

Full text download(s)

Published copy (DOI)


  • F. J. Peaudecerf
  • F. Bunbury
  • V. Bhardwaj
  • Martin Alan Bees
  • A. G. Smith
  • R. E. Goldstein
  • O. A. Croze


Publication details

JournalPhysical Review E
DateAccepted/In press - 31 Jan 2018
DatePublished (current) - 20 Feb 2018
Issue number2
Number of pages14
Original languageEnglish


The exchange of diffusive metabolites is known to control the spatial patterns formed by microbial populations, as revealed by recent studies in the laboratory. However, the matrices used, such as agarose pads, lack the structured geometry of many natural microbial habitats, including in the soil or on the surfaces of plants or animals. Here we address the important question of how such geometry may control diffusive exchanges and microbial interaction. We model mathematically mutualistic interactions within a minimal unit of structure: two growing reservoirs linked by a diffusive channel through which metabolites are exchanged. The model is applied to study a synthetic mutualism, experimentally parametrized on a model algal-bacterial co-culture. Analytical and numerical solutions of the model predict conditions for the successful establishment of remote mutualisms, and how this depends, often counterintuitively, on diffusion geometry. We connect our findings to understanding complex behavior in synthetic and naturally occurring microbial communities.

Discover related content

Find related publications, people, projects, datasets and more using interactive charts.

View graph of relations