The Tunable Activation Threshold hypothesis of T Cells is investigated through computational modelling of T cell signalling pathways. Modelling techniques involving the pi-calculus and the PRISM model checker are presented, and are applied to produce a stochastic model of T cell signalling. Initial results which demonstrate tuning of T cells are presented.
|Number of pages||12|
|Journal||7th International Conference on Artificial Immune Systems (ICARIS)|
|Publication status||Published - Aug 2008|
- LIGAND DISCRIMINATION