Research output: Contribution to journal › Article › peer-review
1.53 MB, PDF document
Journal | Organic Letters |
---|---|
Date | Accepted/In press - 15 Jan 2020 |
Date | E-pub ahead of print - 15 Jan 2020 |
Date | Published (current) - 7 Feb 2020 |
Issue number | 3 |
Volume | 22 |
Number of pages | 7 |
Pages (from-to) | 1175–1181 |
Early online date | 15/01/20 |
Original language | English |
The polycyclic core of the akuammiline alkaloids can be synthesized from simple tryptamine and tryptophol derivatives via a Ag(I)-catalyzed enantioselective dearomative cyclization cascade sequence. The complex tetracyclic scaffolds are prepared via a rapid, versatile, three-step modular synthesis from simple commercially available indole derivatives in high yields and enantiomeric excess (up to 99% yield and >99% ee).
© 2020 American Chemical Society.
Project: Research project (funded) › Research
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