Abstract
Unsymmetrical derivatives of the versatile molecule cis, cis-1,3,5-triaminocyclohexane (tach) have been prepared using a new metal-promoted synthesis to give the mono N-substituted tach ligands. This new method enables the synthesis of these molecules selectively and in good yields and purity. (c) 2005 Elsevier Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 6441-6443 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 46 |
Issue number | 38 |
DOIs | |
Publication status | Published - 19 Sept 2005 |
Keywords
- triaminocyclohexane
- nickel
- biomimetic
- ANTI-ANGIOGENIC THERAPY
- N-PYRIDYL DERIVATIVES
- COPPER(II) COMPLEX
- TRIAMINE LIGANDS
- CIS,CIS-1,3,5-TRIAMINOCYCLOHEXANE
- AGENTS
- CYTOTOXICITY
- HYDROLYSIS
- CHELATION
- BINDING