New weapons explosive exhibits persistent toxicity in plants

Nicola Claire Oates; Edward Nay; Timothy J Cary; Liz Rylott; Neil Charles Bruce

doi:10.1038/s41477-024-01863-0

New weapons explosive exhibits persistent toxicity in plants

Nicola Claire Oates, Edward Nay, Timothy J Cary, Liz Rylott^*, Neil Charles Bruce^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Explosives are widespread, toxic and persistent environmental pollutants. 2,4-Dinitroanisole (DNAN) is being phased in to replace 2,4,6-trinitrotoluene (TNT) in munitions. Here we demonstrate that only low levels of DNAN are detoxified in Arabidopsis, leaving it to remain as a substrate for monodehydroascorbate reductase 6 mediated chronic phytotoxicity. Enhancing the potential for environmental toxicity, DNAN is readily transported to the aerial tissues exposing this toxin to herbivores and the wider food chain.

Original language	English
Number of pages	18
Journal	Nature Plants
Early online date	28 Nov 2024
DOIs	https://doi.org/10.1038/s41477-024-01863-0
Publication status	E-pub ahead of print - 28 Nov 2024

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10.1038/s41477-024-01863-0Licence: CC BY

New weapons explosive exhibits persistent toxicity in plants
© The Author(s) 2024
Final published version, 3.14 MBLicence: CC BY

Cite this

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AB - Explosives are widespread, toxic and persistent environmental pollutants. 2,4-Dinitroanisole (DNAN) is being phased in to replace 2,4,6-trinitrotoluene (TNT) in munitions. Here we demonstrate that only low levels of DNAN are detoxified in Arabidopsis, leaving it to remain as a substrate for monodehydroascorbate reductase 6 mediated chronic phytotoxicity. Enhancing the potential for environmental toxicity, DNAN is readily transported to the aerial tissues exposing this toxin to herbivores and the wider food chain.

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