TY - JOUR
T1 - Non-parametric statistical thresholding of baseline free MEG beamformer images
AU - Prendergast, Garreth
AU - Johnson, Sam Richard
AU - Hymers, Mark
AU - Woods, Will
AU - Green, Gary George Reginald
PY - 2011/1/15
Y1 - 2011/1/15
N2 - Magnetoencephalography (MEG) provides excellent temporal resolution when examining cortical activity in humans. Inverse methods such as beamforming (a spatial filtering approach) provide the means by which activity at cortical locations can be estimated. To date, the majority of work in this field has been based upon power changes between active and baseline conditions. Recent work, however, has focused upon other properties of the time series data reconstructed by these methods. One such metric, the Source Stability Index (SSI), relates to the consistency of the time series calculated only over an active period without the use of a baseline condition. In this paper we apply non-parametric statistics to SSI volumetric maps of simulation, auditory and somatosensory data in order to provide a robust and principled method of statistical inference in the absence of a baseline condition.
AB - Magnetoencephalography (MEG) provides excellent temporal resolution when examining cortical activity in humans. Inverse methods such as beamforming (a spatial filtering approach) provide the means by which activity at cortical locations can be estimated. To date, the majority of work in this field has been based upon power changes between active and baseline conditions. Recent work, however, has focused upon other properties of the time series data reconstructed by these methods. One such metric, the Source Stability Index (SSI), relates to the consistency of the time series calculated only over an active period without the use of a baseline condition. In this paper we apply non-parametric statistics to SSI volumetric maps of simulation, auditory and somatosensory data in order to provide a robust and principled method of statistical inference in the absence of a baseline condition.
UR - http://www.scopus.com/inward/record.url?scp=78649667998&partnerID=8YFLogxK
U2 - doi:10.1016/j.neuroimage.2010.08.005
DO - doi:10.1016/j.neuroimage.2010.08.005
M3 - Article
SN - 1053-8119
VL - 54
SP - 906
EP - 918
JO - Neuroimage
JF - Neuroimage
IS - 2
ER -