Optimizing biomimetic gelators constructed from amino acid building blocks

Ian A. Coates; Andrew R. Hirst; David K. Smith

doi:10.1021/jo070317i

Optimizing biomimetic gelators constructed from amino acid building blocks

Ian A. Coates, Andrew R. Hirst, David K. Smith

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

[GRAPHICS]

This paper reports the use of a range of amino acids to construct diverse gelators, employing structures in which Boc-protected amino acids are attached to either end of an aliphatic diamine spacer chain. The choice of amino acid determines whether nanoscale self-assembly takes place and controls the properties of the resultant material, while the function of the amino acid (e.g., the optical properties of tryptophan) is translated into the self-assembled nanostructured gel.

Original language	English
Pages (from-to)	3937-3940
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	72
Issue number	10
DOIs	https://doi.org/10.1021/jo070317i
Publication status	Published - 11 May 2007

Keywords

MOLECULAR-WEIGHT HYDROGELATORS
GEL-PHASE MATERIALS
ORGANIC LIQUIDS
TRYPTOPHAN FLUORESCENCE
BOLAFORM AMIDES
DENDRITIC GEL
ONE-COMPONENT
L-LYSINE
ORGANOGELS
GELATION

Access to Document

10.1021/jo070317i

Cite this

@article{433f0a64d714435595461646583422f6,

title = "Optimizing biomimetic gelators constructed from amino acid building blocks",

abstract = "[GRAPHICS]This paper reports the use of a range of amino acids to construct diverse gelators, employing structures in which Boc-protected amino acids are attached to either end of an aliphatic diamine spacer chain. The choice of amino acid determines whether nanoscale self-assembly takes place and controls the properties of the resultant material, while the function of the amino acid (e.g., the optical properties of tryptophan) is translated into the self-assembled nanostructured gel.",

keywords = "MOLECULAR-WEIGHT HYDROGELATORS, GEL-PHASE MATERIALS, ORGANIC LIQUIDS, TRYPTOPHAN FLUORESCENCE, BOLAFORM AMIDES, DENDRITIC GEL, ONE-COMPONENT, L-LYSINE, ORGANOGELS, GELATION",

author = "Coates, {Ian A.} and Hirst, {Andrew R.} and Smith, {David K.}",

year = "2007",

month = may,

day = "11",

doi = "10.1021/jo070317i",

language = "English",

volume = "72",

pages = "3937--3940",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

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TY - JOUR

T1 - Optimizing biomimetic gelators constructed from amino acid building blocks

AU - Coates, Ian A.

AU - Hirst, Andrew R.

AU - Smith, David K.

PY - 2007/5/11

Y1 - 2007/5/11

N2 - [GRAPHICS]This paper reports the use of a range of amino acids to construct diverse gelators, employing structures in which Boc-protected amino acids are attached to either end of an aliphatic diamine spacer chain. The choice of amino acid determines whether nanoscale self-assembly takes place and controls the properties of the resultant material, while the function of the amino acid (e.g., the optical properties of tryptophan) is translated into the self-assembled nanostructured gel.

AB - [GRAPHICS]This paper reports the use of a range of amino acids to construct diverse gelators, employing structures in which Boc-protected amino acids are attached to either end of an aliphatic diamine spacer chain. The choice of amino acid determines whether nanoscale self-assembly takes place and controls the properties of the resultant material, while the function of the amino acid (e.g., the optical properties of tryptophan) is translated into the self-assembled nanostructured gel.

KW - MOLECULAR-WEIGHT HYDROGELATORS

KW - GEL-PHASE MATERIALS

KW - ORGANIC LIQUIDS

KW - TRYPTOPHAN FLUORESCENCE

KW - BOLAFORM AMIDES

KW - DENDRITIC GEL

KW - ONE-COMPONENT

KW - L-LYSINE

KW - ORGANOGELS

KW - GELATION

U2 - 10.1021/jo070317i

DO - 10.1021/jo070317i

M3 - Article

SN - 0022-3263

VL - 72

SP - 3937

EP - 3940

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 10

ER -