Organolithium additions to styrene derivatives .4. Tandem intermolecular-intramolecular carbolithiation as a new route to tetralins

X D Wei, R J K Taylor

Research output: Contribution to journalArticlepeer-review

Abstract

Styrenes bearing unsaturated side chains at the 2-position undergo regioselective carbolithiation of the styrene unit followed by 6-exo-trig or 6-exo-dig cyclisation to produce 1,2-disubstituted tetralins or their unsaturated analogues. (C) 1997 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)6467-6470
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number36
Publication statusPublished - 8 Sept 1997

Keywords

  • CYCLIZATION REACTIONS
  • ACETYLENIC ALKYLLITHIUMS

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