Organolithium additions to styrene derivatives, Part IV: Tandem intermolecular-intramolecular carbolithiation as a new route to tetralins

Xudong Wei; Richard J.K. Taylor

doi:10.1016/S0040-4039(97)01479-2

Organolithium additions to styrene derivatives, Part IV: Tandem intermolecular-intramolecular carbolithiation as a new route to tetralins

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Abstract

Styrenes bearing unsaturated side chains at the 2-position undergo regioselective carbolithiation of the styrene unit followed by 6-exo-trig or 6-exo-dig cyclisation to produce 1,2- disubstituted tetralins or their unsaturated analogues.

Original language	English
Pages (from-to)	6467-6470
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	36
DOIs	https://doi.org/10.1016/S0040-4039(97)01479-2
Publication status	Published - 8 Sept 1997

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title = "Organolithium additions to styrene derivatives, Part IV: Tandem intermolecular-intramolecular carbolithiation as a new route to tetralins",

abstract = "Styrenes bearing unsaturated side chains at the 2-position undergo regioselective carbolithiation of the styrene unit followed by 6-exo-trig or 6-exo-dig cyclisation to produce 1,2- disubstituted tetralins or their unsaturated analogues.",

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AU - Taylor, Richard J.K.

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AB - Styrenes bearing unsaturated side chains at the 2-position undergo regioselective carbolithiation of the styrene unit followed by 6-exo-trig or 6-exo-dig cyclisation to produce 1,2- disubstituted tetralins or their unsaturated analogues.

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Organolithium additions to styrene derivatives, Part IV: Tandem intermolecular-intramolecular carbolithiation as a new route to tetralins

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