Research output: Chapter in Book/Report/Conference proceeding › Chapter
Title of host publication | SARCOMERE AND SKELETAL MUSCLE DISEASE |
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Date | Published - 2008 |
Pages | 192-206 |
Number of pages | 15 |
Publisher | SPRINGER-VERLAG BERLIN |
Place of Publication | BERLIN |
Original language | English |
Model organisms arc vital to our understanding of human muscle biology and disease. The potential of the nematode Caenorhabditis elegans, the fruitfly, Drosophila melanogaster and the zebrafish, Danio rerio, as model genetic organisms for the study of human muscle disease is discussed by examining their muscle biology, muscle genetics and development. The powerful genetic tools available with each organism arc outlined. It is concluded that these organisms have already demonstrated potential in facilitating the study of muscle disease and in screening for therapeutic agents.
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