Abstract
(Chemical Equation Presented). A versatile surface-functionalization strategy applicable to mesoporous silica nanoparticles, which could potentially serve as drug delivery vehicles, is described that makes use of alkoxyamine tethers on the surface of the nanoparticles. A wide variety of carbonyl compounds can be attached readily to these tethers under the mild conditions of oxime ether formation, simply by incubating the chemically modified mesoporous silica nanoparticles with aldehydes or ketones in water.
Original language | English |
---|---|
Pages (from-to) | 2146-2149 |
Number of pages | 4 |
Journal | Organic letters |
Volume | 17 |
Issue number | 9 |
DOIs | |
Publication status | Published - 1 May 2015 |
Bibliographical note
Publisher Copyright:© 2015 American Chemical Society.