P-cymenesulphonyl chloride: A bio-based activating group and protecting group for greener organic synthesis

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A bio-derived protecting/activating group has been synthesized by introducing a sulphonyl chloride group to the aromatic ring of p-cymene derived from citrus peel waste. The resulting p-cymenesulphonyl chloride was evaluated as an activating group by reacting with 1-octanol, 2-octanol, phenol and piperidine, and further reactions of the activated alcohols. The comparison to tosyl chloride demonstrates that the bio-based alternative can be effectively utilized as a direct replacement for the current fossil derived equivalent.

Original languageEnglish
Pages (from-to)1914-1919
Number of pages6
JournalJournal of the Brazilian Chemical Society
Issue number9
Publication statusPublished - 1 Sept 2015


  • Activating group
  • Citrus waste
  • P-cymene
  • Protecting group
  • Sulphonyl chloride

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