Palladium-mediated site-selective Suzuki-Miyaura protein modification at genetically encoded aryl halides

Christopher D. Spicer; Benjamin G. Davis

doi:10.1039/c0cc04970k

Palladium-mediated site-selective Suzuki-Miyaura protein modification at genetically encoded aryl halides

Christopher D. Spicer, Benjamin G. Davis

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Site-specific genetic incorporation of unnatural p-halophenylalanine amino acid residues as 'tags' coupled with Pd(0)-mediated Suzuki-Miyuara 'modification' has been enabled by discovery of an effective small molecule palladium scavenger.

Original language	English
Pages (from-to)	1698-1700
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	6
DOIs	https://doi.org/10.1039/c0cc04970k
Publication status	Published - 14 Feb 2011

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title = "Palladium-mediated site-selective Suzuki-Miyaura protein modification at genetically encoded aryl halides",

abstract = "Site-specific genetic incorporation of unnatural p-halophenylalanine amino acid residues as 'tags' coupled with Pd(0)-mediated Suzuki-Miyuara 'modification' has been enabled by discovery of an effective small molecule palladium scavenger.",

author = "Spicer, {Christopher D.} and Davis, {Benjamin G.}",

year = "2011",

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AU - Spicer, Christopher D.

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N2 - Site-specific genetic incorporation of unnatural p-halophenylalanine amino acid residues as 'tags' coupled with Pd(0)-mediated Suzuki-Miyuara 'modification' has been enabled by discovery of an effective small molecule palladium scavenger.

AB - Site-specific genetic incorporation of unnatural p-halophenylalanine amino acid residues as 'tags' coupled with Pd(0)-mediated Suzuki-Miyuara 'modification' has been enabled by discovery of an effective small molecule palladium scavenger.

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JO - Chemical Communications

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Palladium-mediated site-selective Suzuki-Miyaura protein modification at genetically encoded aryl halides

Abstract

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