Parallel Optimisation of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Chemical Tool

Duncan C. Miller, Tristan Reuillon, Lauren Molyneux, Timothy J. Blackburn, Simon Cook, Noel Edwards, Jane A. Endicott, Bernard T. Golding, Roger J. Griffin, Ian R. Hardcastle, Amy B. Heptinstall, Pamela Lochhead, Mathew P. Martin, Nick Martin, Stephanie M. Myers, David R. Newell, Richard Noble, Laurent J.M. Rigoreau, Huw Thomas, Julie Ann TuckerLan-Zhen Wang, Michael J. Waring, Ai-Ching Wong, Stephen Wedge, Martin Noble, Celine Cano

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)6513-6540
Number of pages27
Issue number9
Early online date25 Apr 2022
Publication statusE-pub ahead of print - 25 Apr 2022

Bibliographical note

© 2022 The Authors. Published by American Chemical Society

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