Five exposures of baboons to the attenuated schistosome vaccine gave greater protection than three exposures, but this attenuation was not sustained when challenge was delayed. Within the scope of the data collected, fecal egg counts and circulating antigen levels did not accurately predict the observed worm burdens. Levels of immunoglobulin G at challenge correlated best with protection, but there was little evidence of a recall response.
|Number of pages||4|
|Journal||Infection and Immunity|
|Publication status||Published - Sep 2004|
Bibliographical noteCopyright © 2004, American Society for Microbiology
- IRRADIATED CERCARIA VACCINE
- CIRCULATING ANODIC ANTIGEN
- PROTECTIVE IMMUNITY