Patient recruitment to a diabetic retinopathy screening trial through optimised patient information materials: an embedded study within a trial (SWAT)

Rebecca Sheridan, Peter Knapp, Peter Bower, Vichithranie Madurasinghe, Deborah Broadbent, Lola Awoyale, Amu Wang, Tracy Moitt, on behalf of the ISDR Trial Group

Research output: Contribution to journalArticlepeer-review


Background: Printed participant information about trials is often technical, long and difficult to navigate. Optimisation and user testing can improve information materials, and may improve participant understanding and rates of recruitment.
Methods: A study within a trial (SWAT) was undertaken within the ISDR trial. Potential participants in the ISDR trial were randomised to receive either the standard trial information or revised information that had been optimised through information design and user testing.
Results: A total of 3,169 patients were randomised in the SWAT. Recruitment rates to the ISDR trial were 25.3% in the optimised information group and 26.1% in the standard information group (odds ratio 0.951; 95% CI 0.752 to 1.201; p=0.672). Clinic attendance rates were 71.6% in the optimised information group and 69.3% in the standard information group (OR 1.145; 95% CI 0.885 to 1.480; p=0.304).
Conclusions: Optimisation of participant information through information design and user testing did not affect rate of recruitment to the host ISDR trial.
Original languageEnglish
Article number779
Number of pages10
Publication statusAccepted/In press - 28 Jul 2020

Bibliographical note

© 2021 Amoaku W.
Open peer review discussion version.

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