By the same authors

Pd-catalysed cross-couplings for the pharmaceutical sector and a move to cutting-edge c-h bond functionalization: Is palladium simply too precious?

Research output: Chapter in Book/Report/Conference proceedingChapter

Published copy (DOI)



Publication details

Title of host publicationGreen and Sustainable Medicinal Chemistry
DatePublished - 2016
Number of pages11
PublisherRoyal Society of Chemistry
Original languageEnglish
ISBN (Electronic)978-1-78262-747-0
ISBN (Print)978-1-78262-467-7

Publication series

NameRSC Green Chemistry
ISSN (Print)17577039
ISSN (Electronic)17577047


The case is made for Pd being a critical metal catalyst for a variety of key pharmaceutical sector reactions. There is a need to make such processes more sustainable, e.g. through catalyst recycling, use of lower catalyst loadings and deployment in sustainable C-H activation reactions that avoid high molecular weight waste side-products. Understanding the role played by higher order Pd species (nanoparticles and clusters) is essential in the future. These and related aspects are discussed within this chapter.

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