Abstract
Conformal poly(allyl alcohol) (PAA) coatings
were grown on a biomedical grade polyurethane scaffold using
pulsed plasma polymerization of the allyl alcohol monomer.
The creation of a continuous wave polymer primer layer
increases the interfacial adhesion and stability of a subsequent
pulsed plasma deposited PAA film. The resulting PAA coatings
are strongly hydrophilic and stable following 7 days incubation
in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast
cell culture, while resisting E. coli biofilm formation.
were grown on a biomedical grade polyurethane scaffold using
pulsed plasma polymerization of the allyl alcohol monomer.
The creation of a continuous wave polymer primer layer
increases the interfacial adhesion and stability of a subsequent
pulsed plasma deposited PAA film. The resulting PAA coatings
are strongly hydrophilic and stable following 7 days incubation
in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast
cell culture, while resisting E. coli biofilm formation.
| Original language | English |
|---|---|
| Pages (from-to) | 88–94 |
| Number of pages | 7 |
| Journal | ACS Biomaterials Science & Engineering |
| Volume | 3 |
| Issue number | 1 |
| Early online date | 28 Dec 2016 |
| DOIs | |
| Publication status | Published - 9 Jan 2017 |
Keywords
- plasma
- polyurethane
- XPS
- biofilm
- polymerization
- fibroblast