Preparation and Application of Green Sustainable Solvent Cyrene

Yadong Wang, Mingfei Dai, Gang Luo, Jiajun Fan, James H. Clark, Shicheng Zhang*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


The bio-based solvent dihydrolevoglucosenone (Cyrene) is a green and sustainable alternative to petroleum-based dipolar aprotic solvents. Cyrene can be prepared from cellulose in a simple two-step process and can be produced in a variety of yields. Cyrene is compatible with a large number of reactions in the chemical industry and can be applied in organic chemistry, biocatalysis, materials chemistry, graphene and lignin processing, etc. It is also green, non-mutagenic and non-toxic, which makes it very promising for applications. In this paper, we have also screened all articles related to Cyrene on the Web of Science and visualised them through Cite Space.

Original languageEnglish
Pages (from-to)2322-2346
Number of pages25
JournalChemistry (Switzerland)
Issue number4
Publication statusPublished - 21 Oct 2023

Bibliographical note

© 2023 by the authors.


  • Cyrene
  • green chemistry
  • levoglucosanone

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