Projects per year
Abstract
The dearomatization of 2-haloindole precursors allows access to indoleninyl halides, a hitherto underexploited functional handle with broad synthetic utility. Indoleninyl iodides have been shown to react via three distinct modes: hydrolysis, nucleophilic substitution, and cross-coupling. This allows a broad array of functionalized spirocyclic indole derivatives to be generated from a common starting material. They are also useful precursors to functionalized quinolines following migratory rearrangement and subsequent derivatization reactions.
Original language | English |
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Pages (from-to) | 6328-6331 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 18 |
Issue number | 24 |
Early online date | 28 Nov 2016 |
DOIs | |
Publication status | Published - 16 Dec 2016 |
Bibliographical note
© 2016 American Chemical Society. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for detailsProjects
- 1 Finished
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Catalytic Asymmetric Dearomative Spirocyclisations
Unsworth, W. P. (Co-investigator)
1/07/15 → 30/06/18
Project: Research project (funded) › Research
Datasets
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Raw data for the paper "Preparation and Reactions of Indoleninyl Halides"
Unsworth, W. P. (Creator), University of York, 28 Apr 2017
DOI: 10.15124/724dbcbe-232f-4095-91ca-894c49282a72
Dataset