Preparation of 2-substituted benzimidazoles and related heterocycles directly from activated alcohols using TOP methodology

C D Wilfred, R J K Taylor

Research output: Contribution to journalArticlepeer-review


A one-pot procedure for preparing 2-substituted benzimidazoles directly from activated alcohols in good to excellent yields using a new Tandem Oxidation Process (TOP) is reported. The use of this methodology to prepare 2-substituted benzoxazoles and 2-substituted benzothiazoles is also described.

Original languageEnglish
Pages (from-to)1628-1630
Number of pages3
Issue number9
Publication statusPublished - 22 Jul 2004


  • 2-substituted benzimidazoles
  • 2-substituted benzoxazoles
  • 2-substituted benzothiazoles
  • Tandem Oxidation Procedure
  • one-pot

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