Research output: Contribution to journal › Literature review › peer-review
Journal | Nature reviews. Molecular cell biology |
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Date | Published - Dec 2002 |
Issue number | 12 |
Volume | 3 |
Number of pages | 8 |
Pages (from-to) | 964-970 |
Original language | English |
It is 20 years since site-directed mutagenesis was first used to modify the active site of an enzyme of known structure and mechanism. Since then, this method has contributed far-reaching insights into catalysis, specificity, stability and folding of proteins. Engineered proteins are now being used in industry and for the improved treatment of human disease.
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