Abstract
The Bu3SnH mediated cyclisation of various N-acryloxy-2-amino-2-cyclohexenones was explored. This predominantly gave rise to bicyclic lactams but the reaction mechanism was shown to depend upon the substitution of the amide double bond. Preliminary studies targeted towards the preparation of bicyclic lactones are also reported. (C) 1998 Elsevier Science Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 13405-13420 |
Number of pages | 16 |
Journal | Tetrahedron |
Volume | 54 |
Issue number | 44 |
Publication status | Published - 29 Oct 1998 |
Keywords
- radicals and radical reactions
- cyclisation
- tin and compounds
- enamides
- O-STANNYL KETYLS
- CYCLIZATION REACTIONS
- HALIDES
- CONVERSION
- LACTAMS