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From the same journal

Randomised controlled trial of cognitive-behavioural therapy in early schizophrenia: acute-phase outcomes

Research output: Contribution to journalArticle


  • S Lewis
  • N Tarrier
  • G Haddock
  • R Bentall
  • P Kinderman
  • D Kingdon
  • R Siddle
  • R Drake
  • J Everitt
  • K Leadley
  • A Benn
  • K Grazebrook
  • C Haley
  • S Akhtar
  • L Davies
  • S Palmer
  • B Faragher
  • G Dunn


Publication details

JournalBritish Journal of Psychiatry
DatePublished - Sep 2002
Number of pages7
Pages (from-to)S91-S97
Original languageEnglish


Background Cognitive-behavioural therapy (CBT) improves persistent psychotic symptoms.

Aims To test the effectiveness of added CBT in accelerating remission from acute psychotic symptoms in early schizophrenia.

Method A 5-week CBT programme plus routine care was compared with supportive counselling plus routine, care and routine care alone in a multi-centre trial randomising 315 people with DSM-IV schizophrenia and related disorders in-their first (83%) or second acute admission. Outcome assessments were blinded.

Results Linear regress ion over 70 days showed predicted trends towards faster improvement in the CBT group. Uncorrected univariate comparisons showed significant benefits at 4 but not 6 weeks for CBTv. routine care alone on Positive and Negative Syndrome Scale total and positive sub-scale, scores and delusion score and benefits v. supportive counselling for auditory hallucinations score.

Conclusions CBT shows transient advantages over routine care alone or supportive counselling in speeding remission from acute symptoms in early schizophrenia.

Declaration of interest None. Funding detailed in Acknowledgements.

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