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From the same journal

Real-World Evidence in Healthcare Decision Making: Global trends and case studies from Latin America

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Real-World Evidence in Healthcare Decision Making : Global trends and case studies from Latin America. / Justo, N.; Espinoza, M.; Ratto, B.; Nicholson, M.; Rosselli, D.; Ovcinnikova, O.; García Martí, S.; Ferraz, M. B.; Langsam, M.; Drummond, M.F.

In: Value in Health, Vol. 22, No. 6, 12.06.2019, p. 739-749.

Research output: Contribution to journalArticle

Harvard

Justo, N, Espinoza, M, Ratto, B, Nicholson, M, Rosselli, D, Ovcinnikova, O, García Martí, S, Ferraz, MB, Langsam, M & Drummond, MF 2019, 'Real-World Evidence in Healthcare Decision Making: Global trends and case studies from Latin America', Value in Health, vol. 22, no. 6, pp. 739-749. https://doi.org/10.1016/j.jval.2019.01.014

APA

Justo, N., Espinoza, M., Ratto, B., Nicholson, M., Rosselli, D., Ovcinnikova, O., ... Drummond, M. F. (2019). Real-World Evidence in Healthcare Decision Making: Global trends and case studies from Latin America. Value in Health, 22(6), 739-749. https://doi.org/10.1016/j.jval.2019.01.014

Vancouver

Justo N, Espinoza M, Ratto B, Nicholson M, Rosselli D, Ovcinnikova O et al. Real-World Evidence in Healthcare Decision Making: Global trends and case studies from Latin America. Value in Health. 2019 Jun 12;22(6):739-749. https://doi.org/10.1016/j.jval.2019.01.014

Author

Justo, N. ; Espinoza, M. ; Ratto, B. ; Nicholson, M. ; Rosselli, D. ; Ovcinnikova, O. ; García Martí, S. ; Ferraz, M. B. ; Langsam, M. ; Drummond, M.F. / Real-World Evidence in Healthcare Decision Making : Global trends and case studies from Latin America. In: Value in Health. 2019 ; Vol. 22, No. 6. pp. 739-749.

Bibtex - Download

@article{b0e7f6f602ce467c9bd7100ed733d772,
title = "Real-World Evidence in Healthcare Decision Making: Global trends and case studies from Latin America",
abstract = "Objectives: Real-world evidence (RWE) is increasingly used to inform health technology assessments (HTAs) for resource allocation, which are valuable tools for emerging economies such as in America. However, the characteristics and uses in South America are unknown. This study aims to identify sources, characteristics and uses of RWE in Argentina, Brazil, Colombia and Chile, and evaluate the context-specific challenges. The implications for future regulation and responsible management of RWE in the region are also considered.Methods: A systematic literature review, database mapping, and targeted grey literature search were conducted to identify the sources and characteristics of RWE. Findings were validated by key opinion leaders attending workshops in four South American countries.Results: A database mapping exercise revealed 407 unique databases. Geographic scope, database type, population and outcomes captured were reported. Characteristics of National Health Information Systems show efforts to collect interoperable data from service providers, insurers and government agencies, but that initiatives are hampered by fragmentation, lack of stewardship and resources. RWE is mainly used in South America for pharmacovigilance and as pure academic research, but less so for HTA decision-making or pricing negotiations and not at all to inform early access schemes. Conclusions: The quality of data collected in real-world in the case-study countries varies and RWE is not consistently used in healthcare decision-making. Authors recommend that future studies monitor the impact of digitalisation, and the potential effects of access to RWE on the quality of patient care.",
keywords = "big data, epidemiology, health policy, Health Technology Assessment, Latin America, real-world evidence",
author = "N. Justo and M. Espinoza and B. Ratto and M. Nicholson and D. Rosselli and O. Ovcinnikova and {Garc{\'i}a Mart{\'i}}, S. and Ferraz, {M. B.} and M. Langsam and M.F. Drummond",
note = "{\circledC} 2019, ISPOR–The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc",
year = "2019",
month = "6",
day = "12",
doi = "10.1016/j.jval.2019.01.014",
language = "English",
volume = "22",
pages = "739--749",
journal = "Value in Health",
issn = "1098-3015",
publisher = "Elsevier Inc.",
number = "6",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Real-World Evidence in Healthcare Decision Making

T2 - Value in Health

AU - Justo, N.

AU - Espinoza, M.

AU - Ratto, B.

AU - Nicholson, M.

AU - Rosselli, D.

AU - Ovcinnikova, O.

AU - García Martí, S.

AU - Ferraz, M. B.

AU - Langsam, M.

AU - Drummond, M.F.

N1 - © 2019, ISPOR–The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc

PY - 2019/6/12

Y1 - 2019/6/12

N2 - Objectives: Real-world evidence (RWE) is increasingly used to inform health technology assessments (HTAs) for resource allocation, which are valuable tools for emerging economies such as in America. However, the characteristics and uses in South America are unknown. This study aims to identify sources, characteristics and uses of RWE in Argentina, Brazil, Colombia and Chile, and evaluate the context-specific challenges. The implications for future regulation and responsible management of RWE in the region are also considered.Methods: A systematic literature review, database mapping, and targeted grey literature search were conducted to identify the sources and characteristics of RWE. Findings were validated by key opinion leaders attending workshops in four South American countries.Results: A database mapping exercise revealed 407 unique databases. Geographic scope, database type, population and outcomes captured were reported. Characteristics of National Health Information Systems show efforts to collect interoperable data from service providers, insurers and government agencies, but that initiatives are hampered by fragmentation, lack of stewardship and resources. RWE is mainly used in South America for pharmacovigilance and as pure academic research, but less so for HTA decision-making or pricing negotiations and not at all to inform early access schemes. Conclusions: The quality of data collected in real-world in the case-study countries varies and RWE is not consistently used in healthcare decision-making. Authors recommend that future studies monitor the impact of digitalisation, and the potential effects of access to RWE on the quality of patient care.

AB - Objectives: Real-world evidence (RWE) is increasingly used to inform health technology assessments (HTAs) for resource allocation, which are valuable tools for emerging economies such as in America. However, the characteristics and uses in South America are unknown. This study aims to identify sources, characteristics and uses of RWE in Argentina, Brazil, Colombia and Chile, and evaluate the context-specific challenges. The implications for future regulation and responsible management of RWE in the region are also considered.Methods: A systematic literature review, database mapping, and targeted grey literature search were conducted to identify the sources and characteristics of RWE. Findings were validated by key opinion leaders attending workshops in four South American countries.Results: A database mapping exercise revealed 407 unique databases. Geographic scope, database type, population and outcomes captured were reported. Characteristics of National Health Information Systems show efforts to collect interoperable data from service providers, insurers and government agencies, but that initiatives are hampered by fragmentation, lack of stewardship and resources. RWE is mainly used in South America for pharmacovigilance and as pure academic research, but less so for HTA decision-making or pricing negotiations and not at all to inform early access schemes. Conclusions: The quality of data collected in real-world in the case-study countries varies and RWE is not consistently used in healthcare decision-making. Authors recommend that future studies monitor the impact of digitalisation, and the potential effects of access to RWE on the quality of patient care.

KW - big data

KW - epidemiology

KW - health policy

KW - Health Technology Assessment

KW - Latin America

KW - real-world evidence

U2 - 10.1016/j.jval.2019.01.014

DO - 10.1016/j.jval.2019.01.014

M3 - Article

VL - 22

SP - 739

EP - 749

JO - Value in Health

JF - Value in Health

SN - 1098-3015

IS - 6

ER -