Recent Advances in Green Synthesis of Ag NPs for Extenuating Antimicrobial Resistance

Simerjeet Parmar, Harwinder Kaur, Jagpreet Singh*, Avtar Singh Matharu, Seeram Ramakrishna, Mikhael Bechelany

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Combating antimicrobial resistance (AMR) is an on-going global grand challenge, as recognized by several UN Sustainable Development Goals. Silver nanoparticles (Ag NPs) are well-known for their efficacy against antimicrobial resistance, and a plethora of green synthetic methodologies now exist in the literature. Herein, this review evaluates recent advances in biological approaches for Ag NPs, and their antimicrobial potential of Ag NPs with mechanisms of action are explored deeply. Moreover, short and long-term potential toxic effects of Ag NPs on animals, the environment, and human health are briefly discussed. Finally, we also provide a summary of the current state of the research and future challenges on a biologically mediated Ag-nanostructures-based effective platform for alleviating AMR.

Original languageEnglish
Article number1115
Number of pages22
Issue number7
Publication statusPublished - 28 Mar 2022

Bibliographical note

Funding Information:
The authors gratefully acknowledge Chandigarh University, Mohali, Sri Guru Granth Sahib World University, Punjab (India), University of York, UK, National University of Singapore, Singapore and University of Montpellier, France for providing necessary resources.

Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.


  • antimicrobial resistance
  • environmental
  • green synthesis
  • silver NP’s

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