Regenerative medicine in urology

Felix Wezel, Jennifer Southgate, David F. M. Thomas

Research output: Contribution to journalLiterature reviewpeer-review


The term 'regenerative medicine' encompasses strategies for restoring or renewing tissue or organ function by: (i) in vivo tissue repair by in-growth of host cells into an acellular natural or synthetic biomaterial, (ii) implantation of tissue 'engineered' in vitro by seeding cultured cells into a biomaterial scaffold, and (iii) therapeutic cloning and stem cell-based tissue regeneration. In this article, we review recent developments underpinning the emerging science of regenerative medicine and critically assess where successful implementation of novel regenerative medicine approaches into urology practice might genuinely transform the quality of life of affected individuals. We advocate the need for an evidence-based approach supported by strong science and clinical objectivity.

Original languageEnglish
Pages (from-to)1046-1065
Number of pages20
JournalBJU International
Issue number7
Publication statusPublished - Oct 2011

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