Regression methods for cost-effectiveness analysis with censored data

A.R. Willan, D.Y. Lin, A. Manca

Research output: Contribution to journalArticlepeer-review

Abstract

A system of seemingly unrelated regression equations is proposed for prognostic factor adjustment and subgroup analysis when comparing two groups in a cost-effectiveness analysis with censored data. Because of the induced dependent censoring on costs and quality-adjusted survival, inverse probability weighting is employed for parameter estimation. The method is illustrated with data from two recent examples using both survival time and quality-adjusted survival time as the measures of effectiveness. Copyright (C) 2004 John Wiley Sons, Ltd.

Original languageEnglish
Pages (from-to)131-145
Number of pages15
JournalStatistics in Medicine
Volume24
Issue number1
DOIs
Publication statusPublished - 15 Jan 2005

Keywords

  • regression
  • censored data
  • cost-effectiveness
  • incremental net benefit
  • inverse probability weighting
  • QUALITY-ADJUSTED SURVIVAL
  • IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR
  • RANDOMIZED CLINICAL-TRIALS
  • ESTIMATING MEDICAL COSTS
  • INCREMENTAL NET BENEFIT
  • CONFIDENCE-INTERVALS
  • EFFECTIVENESS RATIOS
  • HEALTH
  • TIME
  • HYSTERECTOMY

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