Relative effectiveness assessment of pharmaceuticals: similarities and differences in 29 jurisdictions

Sarah Kleijnen, Elisabeth George, Scott Goulden, Anne d'Andon, Pauline Vitré, Boguslawa Osińska, Rafal Rdzany, Steffen Thirstrup, Maria Belen Corbacho Martin, Bence Z Nagy, Hubert G Leufkens, Anthonius de Boer, Wim G Goettsch

Research output: Contribution to journalArticlepeer-review


Assessment of the effectiveness compared with alternative treatment(s) plays an important role in many jurisdictions in determining the reimbursement status of pharmaceuticals. This type of assessment is often referred to as a relative effectiveness assessment (REA) and is carried out by many jurisdictions. Increased sharing of information across jurisdictions may save costs and reduce duplication. The objective of this study was to explore the main similarities and differences in the major methodological aspects of REA in multiple jurisdictions.
Original languageEnglish
Pages (from-to)954-60
Number of pages7
JournalValue in Health
Issue number6
Publication statusPublished - Sept 2012

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