Response to discussant comments on “NMA, the first 20 years”

A. E. Ades*, Nicky J. Welton, Sofia Dias, Deborah M. Caldwell, David M. Phillippo

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

Abstract

We respond to discussant comments on our paper “Twenty years of network meta-analysis: Continuing controversies and recent developments” (https://doi.org/10.1002/jrsm.1700) and raise some additional points for consideration, including: the way in which methodological guidance is generated; integration of the estimand framework with evidence synthesis; and implications of the European Joint Clinical Assessment. We ask: what properties are required of population adjustment methods to enable transparent and consistent decision-making? We also ask why individual patient data is not routinely made available to re-imbursement authorities and clinical guideline developers.

Original languageEnglish
Number of pages7
JournalResearch Synthesis Methods
Early online date26 Jul 2024
DOIs
Publication statusE-pub ahead of print - 26 Jul 2024

Bibliographical note

Publisher Copyright:
© 2024 The Author(s). Research Synthesis Methods published by John Wiley & Sons Ltd.

Keywords

  • decision making
  • estimand framework
  • network meta-analysis
  • population-adjustment
  • uncertainty

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