Rethinking vector immunology: The role of environmental temperature in shaping resistance

TY - JOUR

T1 - Rethinking vector immunology

T2 - The role of environmental temperature in shaping resistance

AU - Murdock, Courtney C.

AU - Paaijmans, Krijn P.

AU - Cox-Foster, Diana

AU - Read, Andrew F.

AU - Thomas, Matthew B.

PY - 2012/12

Y1 - 2012/12

N2 - Recent ecological research has revealed that environmental factors can strongly affect insect immunity and influence the outcome of host-parasite interactions. To date, however, most studies examining immune function in mosquitoes have ignored environmental variability. We argue that one such environmental variable, temperature, influences both vector immunity and the parasite itself. As temperatures in the field can vary greatly from the ambient temperature in the laboratory, it will be essential to take temperature into account when studying vector immunology.

AB - Recent ecological research has revealed that environmental factors can strongly affect insect immunity and influence the outcome of host-parasite interactions. To date, however, most studies examining immune function in mosquitoes have ignored environmental variability. We argue that one such environmental variable, temperature, influences both vector immunity and the parasite itself. As temperatures in the field can vary greatly from the ambient temperature in the laboratory, it will be essential to take temperature into account when studying vector immunology.

UR - http://www.scopus.com/inward/record.url?scp=84869235043&partnerID=8YFLogxK

U2 - 10.1038/nrmicro2900

DO - 10.1038/nrmicro2900

M3 - Review article

C2 - 23147703

AN - SCOPUS:84869235043

SN - 1740-1526

VL - 10

SP - 869

EP - 876

JO - Nature Reviews Microbiology

JF - Nature Reviews Microbiology

IS - 12

ER -