Rewriting the bacterial glycocalyx via Suzuki-Miyaura cross-coupling

Christopher D. Spicer, Benjamin G. Davis*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Suzuki-Miyaura cross-coupling has been used to couple novel carbohydrate-based boronic acids, site-selectively, to the surface of E. coli at an unnatural amino acid. In this way, benign metal-catalyzed cellular switching allowed modulation of interactions with biomolecular partners via prokaryotic O-glycosylation mimics.

Original languageEnglish
Pages (from-to)2747-2749
Number of pages3
JournalChemical Communications
Volume49
Issue number27
DOIs
Publication statusPublished - 7 Apr 2013

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