This chapter provides guidance on the preparations needed just prior to the collection of individual participant data (IPD) and how to go about establishing and maintaining collaboration with IPD providers. It discusses various aspects that should be considered when preparing to collect IPD. Negotiating and maintaining collaborations with trial investigators and organisations from different countries, settings and disciplines can take considerable time and effort, and requires careful management, but is critical to the success of collaborative IPD meta-analysis projects. A data-sharing agreement outlining the nature of the collaboration, the responsibilities and obligations of each party, and intellectual property arrangements will be supplied with the finalised protocol. The checking and harmonisation of IPD across trials are integral and necessary components of an IPD meta-analysis project. The results of validity checking and risk of bias assessment should be considered together in order to build up an overall picture of the quality of each trial's IPD.
|Title of host publication
|Individual Participant Data Meta-Analysis
|Subtitle of host publication
|a Handbook for Healthcare Research
|Wiley-Blackwell Publishing Ltd
|Number of pages
|Published - 22 Apr 2021
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