SARS-CoV-2 Omicron BA.5 infections in vaccinated persons, rural Uganda

Joseph Mugisha; Bernard Mpairwe; Robert Newton; Matthew Cotten; My V.T. Phan

doi:10.3201/eid2901.220981

SARS-CoV-2 Omicron BA.5 infections in vaccinated persons, rural Uganda

Joseph Mugisha, Bernard Mpairwe, Robert Newton, Matthew Cotten, My V.T. Phan

Health Sciences

Research output: Contribution to journal › Letter › peer-review

Abstract

We describe a cluster of COVID-19 breakthrough infections after vaccination in Kyamulibwa, Kalungu District, Uganda. All but 1 infection were from SARS-CoV-2 Omicron strain BA.5.2.1. We identified 6 distinct genotypes by genome sequencing. Infections were mild, suggesting vaccination is not protective against infection but may limit disease severity.

Original language	English
Pages (from-to)	224-226
Number of pages	3
Journal	Emerging Infectious Disease journal
Volume	29
Issue number	1
DOIs	https://doi.org/10.3201/eid2901.220981
Publication status	Published - Jan 2023

Keywords

COVID-19
SARS-CoV-2
Omicron
infections
Uganda
respiratory infections
zoonoses
coronavirus disease
severe acute respiratory syndrome coronavirus 2
viruses

Access to Document

10.3201/eid2901.220981

https://wwwnc.cdc.gov/eid/article/29/1/22-0981_article

Cite this

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title = "SARS-CoV-2 Omicron BA.5 infections in vaccinated persons, rural Uganda",

abstract = "We describe a cluster of COVID-19 breakthrough infections after vaccination in Kyamulibwa, Kalungu District, Uganda. All but 1 infection were from SARS-CoV-2 Omicron strain BA.5.2.1. We identified 6 distinct genotypes by genome sequencing. Infections were mild, suggesting vaccination is not protective against infection but may limit disease severity.",

keywords = "COVID-19, SARS-CoV-2, Omicron, infections, Uganda, respiratory infections, zoonoses, coronavirus disease, severe acute respiratory syndrome coronavirus 2, viruses",

author = "Joseph Mugisha and Bernard Mpairwe and Robert Newton and Matthew Cotten and Phan, {My V.T.}",

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AU - Cotten, Matthew

AU - Phan, My V.T.

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AB - We describe a cluster of COVID-19 breakthrough infections after vaccination in Kyamulibwa, Kalungu District, Uganda. All but 1 infection were from SARS-CoV-2 Omicron strain BA.5.2.1. We identified 6 distinct genotypes by genome sequencing. Infections were mild, suggesting vaccination is not protective against infection but may limit disease severity.

KW - COVID-19

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KW - Omicron

KW - infections

KW - Uganda

KW - respiratory infections

KW - zoonoses

KW - coronavirus disease

KW - severe acute respiratory syndrome coronavirus 2

KW - viruses

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