Search research publications and outputs

  1. 2019
  2. The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy

    Seed, R. I., Taurozzi, A. J., Wilcock, D. J., Nappo, G., Erb, H. H. H., Read, M. L., Gurney, M., Archer, L. K., Ito, S., Rumsby, M. G., Petrie, J. L., Clayton, A., Maitland, N. J. & Collins, A. T., 26 Mar 2019

    Article in Scientific Reports

  3. 2018
  4. Development of a sample preparation approach to measure the size of nanoparticle aggregates by electron microscopy

    Dudkiewicz, A., Lehner, A., Chaudhry, Q., Molhave, K., Allmaier, G., Tiede, K., Boxall, A. B. A., Hofmann, P. & Lewis, J., 29 Nov 2018

    Article in Particuology

  5. KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice.

    Polson, ES., Kuchler, VB., Abbosh, C., Ross, EM., Mathew, RK., Beard, HA., da Silva, B., Holding, AN., Ballereau, S., Chuntharpursat-Bon, E., Williams, J., Griffiths, HBS., Shao, H., Patel, A., Davies, AJ., Droop, A., Chumas, P., Short, SC., Lorger, M., Gestwicki, JE. & 6 others, Roberts, LD., Bon, RS., Allison, SJ., Zhu, S., Markowetz, F. & Wurdak, H., 15 Aug 2018

    Article in Science Translational Medicine

  6. 2017
  7. 2016
  8. Cyclin A1 and P450 aromatase promote metastatic homing and growth of stem-like prostate cancer cells in the bone marrow

    Miftakhova, R., Hedblom, A., Semenas, J., Robinson, B. D., Simoulis, A., Malm, J., Rizvanov, A., David Heery, D., Mongan, N. P., Maitland, N. J., Allegrucci, C. & Persson, J. L., 15 Apr 2016

    Article in Cancer research

  9. An epigenetic reprogramming strategy to re-sensitize radioresistant prostate cancer cells

    Peitzsch, C., Cojoc, M., Hein, L., Kurth, I., Mӓbert, K., Trautmann, F., Klink, B., Schrock, E., Wirth, M. P., Krause, M., Stakhovsky, E. A., Telegeev, G. D., Novotny, V., Toma, M. I., Muders, M., Baretton, G. B., Frame, F. M., Maitland, N. J., Baumann, M. & Dubrovska, A., 16 Mar 2016

    Article in Cancer research

  10. 2015
  11. miR-25 modulates invasiveness and dissemination of human prostate cancer cells via regulation of αv- and α6 integrin expression

    Zoni, E., van der Horst, G., van de Merbel, A. F., Chen, L., Rane, J. K., Pelger, R. C. M., Collins, A. T., Visakorpi, T., Snaar-Jagalska, B. E., Maitland, N. J. & van der Pluijm, G., 1 Jun 2015

    Article in Cancer research

  12. CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations

    Khanna, A., Rane, J. K., Kivinummi, K. K., Urbanucci, A., Helenius, M. A., Tolonen, T. T., Saramäki, O. R., Latonen, L., Manni, V., Pimanda, J. E., Maitland, N. J., Westermarck, J. & Visakorpi, T., 19 Apr 2015

    Article in Oncotarget

  13. Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy

    Santer, F. R., Erb, H. H. H., Oh, S. J., Handle, F., Feiersinger, G. E., Luef, B., Bu, H., Schäfer, G., Ploner, C., Egger, M., Rane, J. K., Maitland, N. J., Klocker, H., Eder, I. E. & Culig, Z., 20 Mar 2015

    Article in Oncotarget

  14. 2014
  15. 2013
  16. JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells

    Kroon, P., Berry, P. A., Stower, M. J., Rodrigues, G., Mann, V. M., Simms, M., Bhasin, D., Chettiar, S., Li, C., Li, P-K., Maitland, N. J. & Collins, A. T., 3 Jul 2013

    Article in Cancer research

  17. A preclinical xenograft model of prostate cancer using human tumors

    Lawrence, M. G., Taylor, R. A., Toivanen, R., Pedersen, J., Norden, S., Pook, D. W., Frydenberg, M., Papargiris, M. M., Niranjan, B., Richards, M. G., Wang, H., Collins, A. T., Maitland, N. J., Risbridger, G. P. & Australian Prostate Cancer BioResource, 4 Apr 2013

    Article in Nature Protocols

  18. Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells

    Polson, E. S., Lewis, J. L., Celik, H., Mann, V. M., Stower, M. J., Simms, M. S., Rodrigues, G., Collins, A. T. & Maitland, N. J., 27 Mar 2013

    Article in Nature Communications

  19. 2012
  20. Human Epithelial Basal Cells Are Cells of Origin of Prostate Cancer, Independent of CD133 Status (vol 30, pg 1087, 2012)

    Taylor, R. A., Toivanen, R., Frydenberg, M., Pedersen, J., Harewood, L., Collins, A. T., Maitland, N. J., Risbridger, G. P. & Australian Prostate, Aug 2012

    Article in Stem Cells

  21. Human Epithelial Basal Cells Are Cells of Origin of Prostate Cancer, Independent of CD133 Status

    Taylor, R. A., Toivanen, R., Frydenberg, M., Pedersen, J., Harewood, L., Australian Prostate Cancer Bioresource, N. V., Collins, A. T., Maitland, N. J. & Risbridger, G. P., Jun 2012

    Article in Stem cells (Dayton, Ohio)

  22. In Vitro Primary Cell Culture as a Physiologically Relevant Method for Preclinical Testing of Human Oncolytic Adenovirus

    Adamson, R. E., Frazier, A. A., Evans, H., Chambers, K. F., Schenk, E., Essand, M., Birnie, R., Mitry, R. R., Dhawan, A. & Maitland, N. J., 1 Feb 2012

    Article in HUMAN GENE THERAPY

  23. A transductionally retargeted adenoviral vector for virotherapy of Her2/neu-expressing prostate cancer

    Magnusson, M. K., Kraaij, R., Leadley, R. M., De Ridder, C. M. A., van Weerden, W. M., Van Schie, K. A. J., Van der Kroeg, M., Hoeben, R. C., Maitland, N. J. & Lindholm, L., 1 Jan 2012

    Article in HUMAN GENE THERAPY

  24. 2011
  25. Baculoviruses as gene therapy vectors for human prostate cancer

    Rivera-Gonzalez, G. C., Swift, S. L., Dussupt, V., Georgopoulos, L. J. & Maitland, N. J., Jul 2011

    Article in Journal of invertebrate pathology

  26. Use of macrophages to target therapeutic adenovirus to human prostate tumors

    Muthana, M., Giannoudis, A., Scott, S. D., Fang, H-Y., Coffelt, S. B., Morrow, F. J., Murdoch, C., Burton, J., Cross, N., Burke, B., Mistry, R., Hamdy, F., Brown, N. J., Georgopoulos, L., Hoskin, P., Essand, M., Lewis, C. E. & Maitland, N. J., 1 Mar 2011

    Article in Cancer research

  27. 2010
  28. Gene Transfer Vectors Targeted to Human Prostate Cancer: Do We Need Better Preclinical Testing Systems?

    Maitland, N., Chambers, K., Georgopoulos, L., Simpson-Holley, M., Leadley, R., Evans, H., Essand, M., Danielsson, A., van Weerden, W., de Ridder, C., Kraaij, R., Bangma, C. H. & GIANT FP6 Consortium, Jul 2010

    Article in HUMAN GENE THERAPY

  29. Phenotypic effects of HPV-16 E2 protein expression in human keratinocytes

    Burns, J. E., Walker, H. F., Schmitz, C. & Maitland, N. J., Jun 2010

    Article in VIROLOGY

  30. Engineering Macrophages to Synthesize Recombinant Adenoviruses in Hypoxic Areas of Human Prostate Tumours

    Muthana, M., Giannoudis, A., Scott, S. D., Mistry, R., Murdoch, C., Georgeopolous, L., Hamdy, F., Brown, N., Maitland, N. & Lewis, C. E., Apr 2010

    Article in HUMAN GENE THERAPY

  31. 2009
  32. Human prostate stem cells support replication of a prostate-targeted, conditionally replicating adenovirus

    Frazier, A., Carlisle, R., Evans, H., Georgopoulos, L., Thomson, A., Fisher, K., Seymour, L. & Maitland, N., Nov 2009

    Article in HUMAN GENE THERAPY

  33. Preclinical evaluation of innate immunity to baculovirus gene therapy vectors in whole human blood

    Georgopoulos, L. J., Elgue, G., Sanchez, J., Dussupt, V., Magotti, P., Lambris, J. D., Tötterman, T. H., Maitland, N. J. & Nilsson, B., Sep 2009

    Article in Molecular immunology

  34. 2008
  35. 2007
  36. A role for the heparin-binding cytokines pleiotrophin and midkine in prostate cancer?

    Rumsby, M., Simmonds, J., Sharrard, M., Bland, M., Rodrigues, G., Stower, M. & Maitland, N., Sep 2007

    Article in BJU International

  37. 2006
  38. Use of the PSA enhancer core element to modulate the expression of prostate- and non-prostate-specific basal promoters in a lentiviral vector context

    Chapel-Fernandes, S., Jordier, F., Lauro, F., Maitland, N., Chiaroni, J., de Micco, P., Mannoni, P. & Bagnis, C., Oct 2006

    Article in Cancer gene therapy

  39. 2005
  40. Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues

    Riddick, A. C. P., Shukla, C. J., Pennington, C. J., Bass, R., Nuttall, R. K., Hogan, A., Sethia, K. K., Ellis, V., Collins, A. T., Maitland, N. J., Ball, R. Y. & Edwards, D. R., 20 Jun 2005

    Article in British journal of cancer

  41. 2004
  42. CD133, a novel marker for human prostatic epithelial stem cells

    Richardson, G. D., Robson, C. N., Maitland, N., Lang, S. H., Neal, D. E. & Collins, A. T., 15 Jul 2004

    Article in Journal of Cell Science

  43. Optimization of a synthetic beta-catenin-dependent promoter for tumor-specific cancer gene therapy

    Lipinski, K. S., Djeha, H. A., Gawn, J., Cliffe, S., Maitland, N. J., Palmer, D. H., Mountain, A., Irvine, A. S. & Wrighton, C. J., Jul 2004

    Article in Molecular therapy

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