Search research publications and outputs

  1. 2019
  2. The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy

    Seed, R. I., Taurozzi, A. J., Wilcock, D. J., Nappo, G., Erb, H. H. H., Read, M. L., Gurney, M., Archer, L. K., Ito, S., Rumsby, M. G., Petrie, J. L., Clayton, A., Maitland, N. J. & Collins, A. T., 26 Mar 2019

    Article in Scientific Reports

  3. 2018
  4. 2017
  5. 2016
  6. Cyclin A1 and P450 aromatase promote metastatic homing and growth of stem-like prostate cancer cells in the bone marrow

    Miftakhova, R., Hedblom, A., Semenas, J., Robinson, B. D., Simoulis, A., Malm, J., Rizvanov, A., David Heery, D., Mongan, N. P., Maitland, N. J., Allegrucci, C. & Persson, J. L., 15 Apr 2016

    Article in Cancer research

  7. An epigenetic reprogramming strategy to re-sensitize radioresistant prostate cancer cells

    Peitzsch, C., Cojoc, M., Hein, L., Kurth, I., Mӓbert, K., Trautmann, F., Klink, B., Schrock, E., Wirth, M. P., Krause, M., Stakhovsky, E. A., Telegeev, G. D., Novotny, V., Toma, M. I., Muders, M., Baretton, G. B., Frame, F. M., Maitland, N. J., Baumann, M. & Dubrovska, A., 16 Mar 2016

    Article in Cancer research

  8. 2015
  9. miR-25 modulates invasiveness and dissemination of human prostate cancer cells via regulation of αv- and α6 integrin expression

    Zoni, E., van der Horst, G., van de Merbel, A. F., Chen, L., Rane, J. K., Pelger, R. C. M., Collins, A. T., Visakorpi, T., Snaar-Jagalska, B. E., Maitland, N. J. & van der Pluijm, G., 1 Jun 2015

    Article in Cancer research

  10. CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations

    Khanna, A., Rane, J. K., Kivinummi, K. K., Urbanucci, A., Helenius, M. A., Tolonen, T. T., Saramäki, O. R., Latonen, L., Manni, V., Pimanda, J. E., Maitland, N. J., Westermarck, J. & Visakorpi, T., 19 Apr 2015

    Article in Oncotarget

  11. Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy

    Santer, F. R., Erb, H. H. H., Oh, S. J., Handle, F., Feiersinger, G. E., Luef, B., Bu, H., Schäfer, G., Ploner, C., Egger, M., Rane, J. K., Maitland, N. J., Klocker, H., Eder, I. E. & Culig, Z., 20 Mar 2015

    Article in Oncotarget

  12. 2014
  13. 2013
  14. JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells

    Kroon, P., Berry, P. A., Stower, M. J., Rodrigues, G., Mann, V. M., Simms, M., Bhasin, D., Chettiar, S., Li, C., Li, P-K., Maitland, N. J. & Collins, A. T., 3 Jul 2013

    Article in Cancer research

  15. A preclinical xenograft model of prostate cancer using human tumors

    Lawrence, M. G., Taylor, R. A., Toivanen, R., Pedersen, J., Norden, S., Pook, D. W., Frydenberg, M., Papargiris, M. M., Niranjan, B., Richards, M. G., Wang, H., Collins, A. T., Maitland, N. J., Risbridger, G. P. & Australian Prostate Cancer BioResource, 4 Apr 2013

    Article in Nature Protocols

  16. Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells

    Polson, E. S., Lewis, J. L., Celik, H., Mann, V. M., Stower, M. J., Simms, M. S., Rodrigues, G., Collins, A. T. & Maitland, N. J., 27 Mar 2013

    Article in Nature Communications

  17. 2012
  18. Human Epithelial Basal Cells Are Cells of Origin of Prostate Cancer, Independent of CD133 Status (vol 30, pg 1087, 2012)

    Taylor, R. A., Toivanen, R., Frydenberg, M., Pedersen, J., Harewood, L., Collins, A. T., Maitland, N. J., Risbridger, G. P. & Australian Prostate, Aug 2012

    Article in Stem Cells

  19. Human Epithelial Basal Cells Are Cells of Origin of Prostate Cancer, Independent of CD133 Status

    Taylor, R. A., Toivanen, R., Frydenberg, M., Pedersen, J., Harewood, L., Australian Prostate Cancer Bioresource, N. V., Collins, A. T., Maitland, N. J. & Risbridger, G. P., Jun 2012

    Article in Stem cells (Dayton, Ohio)

  20. In Vitro Primary Cell Culture as a Physiologically Relevant Method for Preclinical Testing of Human Oncolytic Adenovirus

    Adamson, R. E., Frazier, A. A., Evans, H., Chambers, K. F., Schenk, E., Essand, M., Birnie, R., Mitry, R. R., Dhawan, A. & Maitland, N. J., 1 Feb 2012

    Article in HUMAN GENE THERAPY

  21. A transductionally retargeted adenoviral vector for virotherapy of Her2/neu-expressing prostate cancer

    Magnusson, M. K., Kraaij, R., Leadley, R. M., De Ridder, C. M. A., van Weerden, W. M., Van Schie, K. A. J., Van der Kroeg, M., Hoeben, R. C., Maitland, N. J. & Lindholm, L., 1 Jan 2012

    Article in HUMAN GENE THERAPY

  22. 2011
  23. Baculoviruses as gene therapy vectors for human prostate cancer

    Rivera-Gonzalez, G. C., Swift, S. L., Dussupt, V., Georgopoulos, L. J. & Maitland, N. J., Jul 2011

    Article in Journal of invertebrate pathology

  24. Use of macrophages to target therapeutic adenovirus to human prostate tumors

    Muthana, M., Giannoudis, A., Scott, S. D., Fang, H-Y., Coffelt, S. B., Morrow, F. J., Murdoch, C., Burton, J., Cross, N., Burke, B., Mistry, R., Hamdy, F., Brown, N. J., Georgopoulos, L., Hoskin, P., Essand, M., Lewis, C. E. & Maitland, N. J., 1 Mar 2011

    Article in Cancer research

  25. 2010
  26. Gene Transfer Vectors Targeted to Human Prostate Cancer: Do We Need Better Preclinical Testing Systems?

    Maitland, N., Chambers, K., Georgopoulos, L., Simpson-Holley, M., Leadley, R., Evans, H., Essand, M., Danielsson, A., van Weerden, W., de Ridder, C., Kraaij, R., Bangma, C. H. & GIANT FP6 Consortium, Jul 2010

    Article in HUMAN GENE THERAPY

  27. Phenotypic effects of HPV-16 E2 protein expression in human keratinocytes

    Burns, J. E., Walker, H. F., Schmitz, C. & Maitland, N. J., Jun 2010

    Article in VIROLOGY

  28. Engineering Macrophages to Synthesize Recombinant Adenoviruses in Hypoxic Areas of Human Prostate Tumours

    Muthana, M., Giannoudis, A., Scott, S. D., Mistry, R., Murdoch, C., Georgeopolous, L., Hamdy, F., Brown, N., Maitland, N. & Lewis, C. E., Apr 2010

    Article in HUMAN GENE THERAPY

  29. 2009
  30. Human prostate stem cells support replication of a prostate-targeted, conditionally replicating adenovirus

    Frazier, A., Carlisle, R., Evans, H., Georgopoulos, L., Thomson, A., Fisher, K., Seymour, L. & Maitland, N., Nov 2009

    Article in HUMAN GENE THERAPY

  31. Preclinical evaluation of innate immunity to baculovirus gene therapy vectors in whole human blood

    Georgopoulos, L. J., Elgue, G., Sanchez, J., Dussupt, V., Magotti, P., Lambris, J. D., Tötterman, T. H., Maitland, N. J. & Nilsson, B., Sep 2009

    Article in Molecular immunology

  32. 2008
  33. 2007
  34. A role for the heparin-binding cytokines pleiotrophin and midkine in prostate cancer?

    Rumsby, M., Simmonds, J., Sharrard, M., Bland, M., Rodrigues, G., Stower, M. & Maitland, N., Sep 2007

    Article in BJU International

  35. Prostate cancer stem cells: A target for new therapies

    Maitland, N. J., Bryce, S. D., Stower, M. J. & Collins, A. T., 2007, Cancer Stem Cells: Novel Concepts and Prospects for Tumor Therapy. Wiestler, OD., Haendler, B. & Mumberg, D. (eds.). BERLIN: SPRINGER-VERLAG BERLIN, p. 155-179 25 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  36. 2006
  37. Use of the PSA enhancer core element to modulate the expression of prostate- and non-prostate-specific basal promoters in a lentiviral vector context

    Chapel-Fernandes, S., Jordier, F., Lauro, F., Maitland, N., Chiaroni, J., de Micco, P., Mannoni, P. & Bagnis, C., Oct 2006

    Article in Cancer gene therapy

  38. Gene therapy for prostate cancer: Current strategies and new cell-based approaches

    MacRae, E. J., Giannoudis, A., Ryan, R., Brown, N. J., Hamdy, F. C., Maitland, N. & Lewis, C. E., 1 Apr 2006

    Literature review in Prostate

  39. 2005
  40. Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues

    Riddick, A. C. P., Shukla, C. J., Pennington, C. J., Bass, R., Nuttall, R. K., Hogan, A., Sethia, K. K., Ellis, V., Collins, A. T., Maitland, N. J., Ball, R. Y. & Edwards, D. R., 20 Jun 2005

    Article in British journal of cancer

  41. 2004
  42. CD133, a novel marker for human prostatic epithelial stem cells

    Richardson, G. D., Robson, C. N., Maitland, N., Lang, S. H., Neal, D. E. & Collins, A. T., 15 Jul 2004

    Article in Journal of Cell Science

  43. Optimization of a synthetic beta-catenin-dependent promoter for tumor-specific cancer gene therapy

    Lipinski, K. S., Djeha, H. A., Gawn, J., Cliffe, S., Maitland, N. J., Palmer, D. H., Mountain, A., Irvine, A. S. & Wrighton, C. J., Jul 2004

    Article in Molecular therapy

  44. Human papillomaviruses and cancer in Uganda

    Newton, R., Bousarghin, L., Ziegler, J., Casabonne, D., Beral, V., Mbidde, E., Carpenter, L., Parkin, D. M., Wabinga, H., Mbulaiteye, S., Jaffe, H., Touzé, A., Coursaget, P., Sembajwe, V., Kalinaki, M., Byansi, R., Rwatooro, C., Nambooze, S., Tushimiere, B., Byabazaire, N. & 10 othersBitamazire, E., Katabira, E., Mugerwa, J., Tindyebura, D., Ateenyi-Agaba, C., Whitworth, J., Richardson, B., Reeves, G., Weiss, R. & De Cock, K., Apr 2004

    Article in European journal of cancer prevention

  45. Targeting gene therapy for prostate cancer

    Maitland, N. J., Stanbridge, L. J. & Dussupt, V., 2004

    Literature review in Current pharmaceutical design

  46. 2003
  47. 2002
  48. Enhanced expression of vimentin in motile prostate cell lines and in poorly differentiated and metastatic prostate carcinoma

    Lang, S. H., Hyde, C., Reid, I. N., Hitchcock, I. S., Hart, C. A., Bryden, A. A. G., Villette, J-M., Stower, M. J. & Maitland, N. J., 1 Sep 2002

    Article in Prostate

  49. Recombinant adenovirus vector activates and protects human monocyte-derived dendritic cells from apoptosis

    Lundqvist, A., Choudhury, A., Nagata, T., Andersson, T., Quinn, G., Fong, T., Maitland, N., Pettersson, S., Paulie, S. & Pisa, P., Sep 2002

    Article in HUMAN GENE THERAPY

  50. Mutations of the BRAF gene in human cancer

    Davies, H., Bignell, G. R., Cox, C., Stephens, P., Edkins, S., Clegg, S., Teague, J., Woffendin, H., Garnett, M. J., Bottomley, W., Davis, N., Dicks, N., Ewing, R., Floyd, Y., Gray, K., Hall, S., Hawes, R., Hughes, J., Kosmidou, V., Menzies, A. & 32 othersMould, C., Parker, A., Stevens, C., Watt, S., Hooper, S., Wilson, R., Jayatilake, H., Gusterson, B. A., Cooper, C., Shipley, J., Hargrave, D., Pritchard-Jones, K., Maitland, N., Chenevix-Trench, G., Riggins, G. J., Bigner, D. D., Palmieri, G., Cossu, A., Flanagan, A., Nicholson, A., Ho, J. W. C., Leung, S. Y., Yuen, S. T., Weber, B. L., Siegler, H. F., Darrow, T. L., Paterson, H., Marais, R., Marshall, C. J., Wooster, R., Stratton, M. R. & Futreal, P. A., 27 Jun 2002

    Article in Nature

  51. The structure of S100A12 in a hexameric form and its proposed role in receptor signalling

    Moroz, O. V., Antson, A. A., Dodson, E. J., Burrell, H. J., Grist, S. J., Lloyd, R. M., Maitland, N. J., Dodson, G. G., Wilson, K. S., Lukanidin, E. & Bronstein, I. B., Mar 2002

    Article in Acta Crystallographica Section D: Biological Crystallography

  52. 2001
  53. In vitro modelling of the prostate: 3D culture of prostatic cells in matrigel

    Lang, S. H., Stark, M., Hall, J., Hyde, K., Stower, M. & Maitland, N. J., Jul 2001

    Article in British journal of cancer

  54. The dimerization interface of the metastasis-associated protein S100A4 (Mts1) - In vivo and in vitro studies

    Tarabykina, S., Scott, D. J., Herzyk, P., Hill, T. J., Tame, J. R. H., Kriajevska, M., Lafitte, D., Derrick, P. J., Dodson, G. G., Maitland, N. J., Lukanidin, E. M. & Bronstein, I. B., 29 Jun 2001

    Article in Journal of Biological Chemistry

  55. In vitro models to study cellular differentiation and function in human prostate cancers

    Maitland, N. J., Macintosh, C. A., Hall, J., Sharrard, M., Quinn, G. & Lang, S., Jan 2001

    Article in Radiation research

  56. 2000
  57. Structure of the intact transactivation domain of the human papillomavirus E2 protein

    Antson, A. A., Burns, J. E., Moroz, O. V., Scott, D. J., Sanders, C. M., Bronstein, I. B., Dodson, G. G., Wilson, K. S. & Maitland, N. J., 17 Feb 2000

    Article in Nature

  58. 1999
  59. Inhibition of T cell activation by normal human biliary epithelial cells

    Cruickshank, S. M., Southgate, J., Selby, P. J. & Trejdosiewicz, L. K., 1 Dec 1999

    Article in Journal of Hepatology

  60. Human papillomavirus type 16 E2-specific T-helper lymphocyte responses in patients with cervical intraepithelial neoplasia

    Bontkes, H. J., de Gruijl, T. D., Bijl, A., Verheijen, R. H. M., Meijer, C. J. L. M., Scheper, R. J., Stern, P. L., Burns, J. E., Maitland, N. J. & Walboomers, J. M. M., Sep 1999

    Article in Journal of general virology

  61. FGF7/KGF triggers cell transformation and invasion on immortalised human prostatic epithelial PNT1A cells

    Ropiquet, F., Huguenin, S., Villette, J. M., Ronfle, V., Le Brun, G., Maitland, N. J., Cussenot, O., Fiet, J. & Berthon, P., 19 Jul 1999

    Article in International Journal of Cancer

  62. BCL10 is rarely mutated in human prostate carcinoma, small-cell lung cancer, head and neck tumours, renal carcinoma and sarcomas

    Gill, S., Broni, J., Jefferies, S., Osin, P., Kovacs, G., Maitland, N. J., Eeles, R., Edwards, S. M., Dyer, M. J. S., Willis, T. G., Cooper, C. S. & MPT Collaborators, St Georges Hosp Collaborators, Jul 1999

    Article in British journal of cancer

  63. 1998
  64. Expression patterns of the human papillomavirus type 16 transcription factor E2 in low- and high-grade cervical intraepithelial neoplasia

    Maitland, N. J., Conway, S., Wilkinson, N. S., Ramsdale, J., Morris, J. R., Sanders, C. M., Burns, J. E., Stern, P. L. & Wells, M., Nov 1998

    Article in Journal of Pathology

  65. Metastasis-associated Mts1 (S100A4) protein modulates protein kinase C phosphorylation of the heavy chain of nonmuscle myosin

    Kriajevska, M., Tarabykina, S., Bronstein, I., Maitland, N., Lomonosov, M., Hansen, K., Georgiev, G. & Lukanidin, E., 17 Apr 1998

    Article in Journal of Biological Chemistry

  66. 1997
  67. Androgens are not a direct requirement for the proliferation of human prostatic epithelium in vitro

    Berthon, P., Waller, A. S., Villette, J. M., Loridon, L., Cussenot, O. & Maitland, N. J., 10 Dec 1997

    Article in International Journal of Cancer

  68. Differences In serological IgA responses to recombinant baculovirus-derived human papillomavirus E2 protein in the natural history of cervical neoplasia

    RochaZavaleta, L., Jordan, D., Pepper, S., Corbitt, G., Clarke, F., Maitland, N. J., Sanders, C. M., Arrand, J. R., Stern, P. L. & Stacey, S. N., Apr 1997

    Article in British journal of cancer

  69. Co-ordinated changes in expression of cell adhesion molecules in prostate cancer

    Murant, S. J., Handley, J., Stower, M., Reid, N., Cussenot, O. & Maitland, N. J., Feb 1997

    Article in European Journal of Cancer

  70. 1996
  71. 1995
  72. DEMONSTRATION OF SMOKING-RELATED DNA-DAMAGE IN CERVICAL EPITHELIUM AND CORRELATION WITH HUMAN PAPILLOMAVIRUS TYPE-16, USING EXFOLIATED CERVICAL CELLS

    Simons, A. M., Vanherckenrode, C. M., Rodriguez, J. A., Maitland, N., Anderson, M., Phillips, D. H. & Coleman, D. V., Feb 1995

    Article in British journal of cancer

  73. 1994
  74. 1993
  75. 1992
  76. 1990
  77. Identification of a putative RNA helicase in E. coli

    Iggo, R., Picksley, S., Southgate, J., McPheat, J. & Lane, D. P., 19 Oct 1990

    Article in Nucleic Acids Research

  78. 1989
  79. Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ

    Thompson, T. C., Southgate, J., Kitchener, G. & Land, H., 24 Mar 1989

    Article in Cell

  80. 1988
  81. Molecular Biology of Wilm's Tumour

    Shaw, A. P. W., Poirier, V., Finerty, S., Berry, P. J., Mott, M. G. & Maitland, N. J., 1988

    Article in Bristol medico-chirurgical journal (1963)