Search research publications and outputs

  1. 2018
  2. Niche Heterogeneity Impacts Evolution of Myeloproliferative Neoplasms Driven By the Same Oncogenic Pathway

    Korn, C., Rak, J., Garcia-Garcia, A., Fielding, C., Khorshed, R., Gonzalez-Anton, S., Li, J., Norfo, R., Baxter, EJ., McKerrell, T., Roberts, T., Eldaly, H., Godfrey, AL., Castillo-Venzor, A., Kusumbe, A., Mead, AJ., Green, AR., Kent, D., Lo Celso, C. & Mendez-Ferrer, S., 29 Nov 2018

    Article in Blood

  3. The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses

    Bierschenk, D., Monteleone, M., Moghaddas, F., Baker, P. J., Masters, S. L., Boucher, D. & Schroder, K., 4 Oct 2018

    Article in Journal of leukocyte biology

  4. Population dynamics of normal human blood inferred from somatic mutations.

    Lee-Six, H., Øbro, NF., Shepherd, MS., Grossmann, S., Dawson, K., Belmonte, M., Osborne, RJ., Huntly, BJP., Martincorena, I., Anderson, E., O'Neill, L., Stratton, MR., Laurenti, E., Green, AR., Kent, DG. & Campbell, PJ., 27 Sep 2018

    Article in Nature

  5. Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps

    Chen, K. W., Monteleone, M., Boucher, D., Sollberger, G., Ramnath, D., Condon, N. D., von Pein, J. B., Broz, P., Sweet, M. J. & Schroder, K., 24 Aug 2018

    Article in Immunology today

  6. Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal.

    Shepherd, MS., Li, J., Wilson, NK., Oedekoven, CA., Li, J., Belmonte, M., Fink, J., Prick, JCM., Pask, DC., Hamilton, TL., Loeffler, D., Rao, A., Schröder, T., Göttgens, B., Green, AR. & Kent, DG., 23 Aug 2018

    Article in Blood

  7. KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice.

    Polson, ES., Kuchler, VB., Abbosh, C., Ross, EM., Mathew, RK., Beard, HA., da Silva, B., Holding, AN., Ballereau, S., Chuntharpursat-Bon, E., Williams, J., Griffiths, HBS., Shao, H., Patel, A., Davies, AJ., Droop, A., Chumas, P., Short, SC., Lorger, M., Gestwicki, JE. & 6 others, Roberts, LD., Bon, RS., Allison, SJ., Zhu, S., Markowetz, F. & Wurdak, H., 15 Aug 2018

    Article in Science Translational Medicine

  8. Identification of residues in ABCG2 affecting protein trafficking and drug transport, using co-evolutionary analysis of ABCG sequences

    Haider, A. J., Cox, M. H., Jones, N., Goode, A. J., Bridge, K. S., Wong, K., Briggs, D. & Kerr, I. D., 1 Aug 2018

    Article in Bioscience Reports

  9. A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice.

    Dahlin, JS., Hamey, FK., Pijuan-Sala, B., Shepherd, M. S., Lau, WWY., Nestorowa, S., Weinreb, C., Wolock, S., Hannah, R., Diamanti, E., Kent, DG., Göttgens, B. & Wilson, NK., 24 May 2018

    Article in Blood

  10. Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion

    Chen, K. W., Lawlor, K. E., von Pein, J. B., Boucher, D., Gerlic, M., Croker, B. A., Bezbradica, J. S., Vince, J. E. & Schroder, K., 15 May 2018

    Article in Journal of Immunology

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