Search research publications and outputs

  1. 2017
  2. C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

    Lee, Y-B., Baskaran, P., Gomez-Deza, J., Chen, H-J., Nishimura, A. L., Smith, B. N., Troakes, C., Adachi, Y., Stepto, A., Petrucelli, L., Gallo, J-M., Hirth, F., Rogelj, B., Guthrie, S. & Shaw, C. E., 15 Dec 2017

    Article in Human Molecular Genetics

  3. Conserved asymmetry underpins homodimerization of Dicer-associated double-stranded RNA-binding proteins

    Heyam, A., Coupland, C. E., Dégut, C., Haley, R. A., Baxter, N. J., Jakob, L., Aguiar, P. M., Meister, G., Williamson, M. P., Lagos, D. & Plevin, M. J., 1 Dec 2017

    Article in Nucleic Acids Research

  4. Magneto-optic probe measurements in low density-supersonic jets

    Oliver, D. M., White, T. G., Maybe, P., Kühn-Kauffeldt, M., Döhl, L., Bingham, R., Clarke, R., Graham, P., Heathcote, R., Koenig, M., Kuramitsu, Y., Lamb, D. Q., Meinecke, J., Michel, T., Miniati, F., Notley, M. M., Reville, B., Sarkar, S., Sakawa, Y., Schekochihin, A. A. & 4 others, Tzeferacos, P., Woolsey, N., Park, H. S. & Gregori, G., 1 Dec 2017

    Article in Journal of Instrumentation

  5. Valorising faba bean residual biomass: Effect of farming system and planting time on the potential for biofuel production

    Gómez, L. D., Amalfitano, C., Andolfi, A., Simister, R., Somma, S., Ercolano, M. R., Borrelli, C., McQueen-Mason, S. J., Frusciante, L., Cuciniello, A. & Caruso, G., 1 Dec 2017

    Article in Biomass & bioenergy

  6. A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.

    Johnston, C. J. C., Smyth, D. J., Kodali, R. B., White, M. P. J., Harcus, Y., Filbey, K. J., Hewitson, J. P., Hinck, C. S., Ivens, A., Kemter, A. M., Kildemoes, A. O., Le Bihan, T., Soares, D. C., Anderton, S. M., Brenn, T., Wigmore, S. J., Woodcock, H. V., Chambers, R. C., Hinck, A. P., McSorley, H. J. & 1 others, Maizels, R. M., 23 Nov 2017

    Article in Nature Communications

  7. Assembly and comparison of two closely related Brassica napus genomes

    Bayer, P. E., Hurgobin, B., Golicz, A. A., Chan, C-K. K., Yuan, Y., Lee, H., Renton, M., Meng, J., Li, R., Long, Y., Zou, J., Bancroft, I., Chalhoub, B., King, G. J., Batley, J. & Edwards, D., 21 Nov 2017

    Article in Plant biotechnology journal

  8. Spontaneous development of Epstein-Barr Virus associated human lymphomas in a prostate cancer xenograft program

    Taurozzi, A. J., Beekharry, R., Wantoch, M., Labarthe, M-C., Walker, H. F., Seed, R. I., Simms, M. S., Rodrigues, G., Bradford, J., van der Horst, G., van der Pluijm, G. & Collins, A. T., 16 Nov 2017

    Article in PLoS ONE

  9. A transatlantic perspective on 20 emerging issues in biological engineering

    Wintle, B. C., Boehm, C. R., Rhodes, C., Molloy, J. C., Millett, P., Adam, L., Breitling, R., Carlson, R., Casagrande, R., Dando, M., Doubleday, R., Drexler, E., Edwards, B., Ellis, T., Evans, N. G., Hammond, R., Haseloff, J., Kahl, L., Kuiken, T., Lichman, B. R. & 9 others, Matthewman, C. A., Napier, J. A., ÓhÉigeartaigh, S. S., Patron, N. J., Perello, E., Shapira, P., Tait, J., Takano, E. & Sutherland, W. J., 14 Nov 2017

    Article in eLife

  10. Simultaneous two-color imaging in digital holographic microscopy

    Farthing, N. E., Findlay, R. C., Jikeli, J. F., Walrad, P. B., Bees, M. A. & Wilson, L. G., 13 Nov 2017

    Article in Optics Express

  11. An oleuropein β-glucosidase from olive fruit is involved in determining the phenolic composition of virgin olive oil

    Velazquez-Palmero, D., Romero-Segura, C., Garcia-Rodriguez, R., Hernandez, M. L., Vaistij, F. E., Graham, I. A., Perez, A. G. & Martinez-Rivas, J. M., 7 Nov 2017

    Article in Frontiers in Plant Science

  12. Empirical and theoretical investigation into the potential impacts of insecticide resistance on the effectiveness of insecticide-treated bed nets

    Glunt, K. D., Coetzee, M., Huijben, S., Koffi, A. A., Lynch, P. A., N'Guessan, R., Oumbouke, W. A., Sternberg, E. D. & Thomas, M. B., 7 Nov 2017

    Article in Evolutionary applications

  13. Synergistic malaria vaccine combinations identified by systematic antigen screening.

    Bustamante, L. Y., Powell, G. T., Lin, Y-C., Macklin, M. D., Cross, N., Kemp, A., Cawkill, P., Sanderson, T., Crosnier, C., Muller-Sienerth, N., Doumbo, O. K., Traore, B., Crompton, P. D., Cicuta, P., Tran, T. M., Wright, G. J. & Rayner, J. C., 7 Nov 2017

    Article in Proceedings of the National Academy of Sciences USA

  14. Genome-wide linkage and association study implicates the 10q26 region as a major genetic contributor to primary nonsyndromic vesicoureteric reflux

    Darlow, J. M., Darlay, R., Dobson, M. G., Stewart, A., Charoen, P., Southgate, J., Baker, S. C., Xu, Y., Hunziker, M., Lambert, H. J., Green, A. J., Santibanez-Koref, M., Sayer, J. A., Goodship, T. H. J., Puri, P., Woolf, A. S., Kenda, R. B., Barton, D. E. & Cordell, H. J., 6 Nov 2017

    Article in Scientific Reports

  15. A Plant-Feeding Nematode Indirectly Increases the Fitness of an Aphid

    Hoysted, G. A., Lilley, C. J., Field, K. J., Dickinson, M., Hartley, S. E. & Unwin, P. E., 3 Nov 2017

    Article in Frontiers in Plant Science

  16. Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions.

    Payne, R. O., Silk, S. E., Elias, S. C., Miura, K., Diouf, A., Galaway, F., de Graaf, H., Brendish, N. J., Poulton, I. D., Griffiths, O. J., Edwards, N. J., Jin, J., Labbé, G. M., Alanine, D. G., Siani, L., Di Marco, S., Roberts, R., Green, N., Berrie, E., Ishizuka, A. S. & 22 others, Nielsen, C. M., Bardelli, M., Partey, F. D., Ofori, M. F., Barfod, L., Wambua, J., Murungi, L. M., Osier, F. H., Biswas, S., McCarthy, J. S., Minassian, A. M., Ashfield, R., Viebig, N. K., Nugent, F. L., Douglas, A. D., Vekemans, J., Wright, G. J., Faust, S. N., Hill, A. V., Long, C. A., Lawrie, A. M. & Draper, S. J., 2 Nov 2017

    Article in JCI Insight

  17. Targeted metatranscriptomics of compost derived consortia reveals a GH11 exerting an unusual exo-1,4-β-xylanase activity

    Mello, B., Alessi, A., Riaño-Pachón, D., deAzevedo, E., Guimarães, F., Espirito Santo, M., McQueen Mason, S. J., Bruce, N. C. & Polikarpov, I., 2 Nov 2017

    Article in Biotechnology for biofuels

  18. Conducting robust ecological analyses with climate data

    Suggitt, A., Platts, P. J., Barata, I. M., Bennie, J. J., Burgess, M. D., Bystriakova, N., Duffield, S., Ewing, S. R., Gillingham, P. K., Harper, A. B., Hartley, A. J., Hemming, D. L., Maclean, I. M. D., Maltby, K., Marshall, H. H., Morecroft, M. D., Pearce-Higgins, J. W., Pearce-Kelly, P., Phillimore, A. B., Price, J. T. & 4 others, Pyke, A., Stewart, J. A., Warren, R. & Hill, J. K., 1 Nov 2017

    Article in Oikos

  19. Increased sequencing depth does not increase captured diversity of arbuscular mycorrhizal fungi

    Vasar, M., Andreson, R., Davison, J., Jairus, T., Moora, M., Remm, M., Young, J. P. W., Zobel, M. & Öpik, M., 1 Nov 2017

    Article in MYCORRHIZA

  20. COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal

    Xu, P., Hankins, H. M., MacDonald, C., Erlinger, S. J., Frazier, M. N., Diab, N. S., Piper, R. C., Jackson, L. P., MacGurn, J. A. & Graham, T. R., 31 Oct 2017

    Article in eLife

  21. HpARI protein secreted by a helminth parasite suppresses interleukin-33

    Osbourne, M., Soares, D. C., Vacca, F., Cohen, E. S., Scott, I. C., Gregory, W. F., Smyth, D. J., Toivakka, M., Kemter, A. M., le Bihan, T., Wear, M., Hoving, D., Filbey, K. J., Hewitson, J. P., Henderson, H., Gonzalez-Ciscar, A., Errington, C., Vermeren, S., Astier, A. L., Wallace, W. A. & 4 others, Schwarze, J., Ivens, A. C., Maizels, R. M. & McSorley, H. J., 17 Oct 2017

    Article in Immunity

  22. dOCRL maintains immune cell quiescence in Drosophila by regulating endosomal traffic

    del Signore, S. J., Biber, S. A., Lehmann, K. S., Heimler, S. R., Rosenfeld, B. H., Eskin, T. L., Sweeney, S. & Rodal, A., 13 Oct 2017

    Article in PLoS Genetics

  23. Insect elevational specialization in a tropical biodiversity hotspot

    Macedo, M. V., Monteiro, R. F., Flinte, V., Almeida-Neto, M., Khattar, G., da Silveira, L. F. L., de O Araujo, C., de O Araujo, R., Colares, C., da S Gomes, C. V., Mendes, C., Santos, E. F. & Mayhew, P. J., 11 Oct 2017

    Article in Insect conservation and diversity

  24. Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase

    Lichman, B. R., Sula, A., Pesnot, T., Hailes, H. C., Ward, J. M. & Keep, N. H., 10 Oct 2017

    Article in Biochemistry

  25. Membrane Trafficking Modulation during Entamoeba Encystation

    Herman, E. K., Siegesmund, M. A., Bottery, M. J., van Aerle, R., Shather, M. M., Caler, E., Dacks, J. B. & Van Der Giezen, M., 9 Oct 2017

    Article in Scientific Reports

  26. A pan-tropical analysis of the impacts of forest degradation and conversion on local temperature

    Senior, R. A., Hill, J. K., Gonzalez del Pliego, P., Goode, L. K. & Edwards, D. P., 1 Oct 2017

    Article in Ecology and Evolution

  27. Biotin tagging of MeCP2 in mice reveals contextual insights into the Rett syndrome transcriptome

    Johnson, B. S., Zhao, Y-T., Fasolino, M., Lamonica, J. M., Kim, Y. J., Georgakilas, G., Wood, K. H., Bu, D., Cui, Y., Goffin, D. L., Vahedi, G., Kim, T. H. & Zhou, Z., 1 Oct 2017

    Article in Nature Medicine

  28. Circadian rhythms vary over the growing season and correlate with fitness components

    Rubin, M., Brock, M., Davis, A. M., German, Z., Knapp, M., Welch, S., Harmer, S. L., Maloof, J. N., Davis, S. J. & Weinig, C., 1 Oct 2017

    Article in Molecular Ecology

  29. Complex roles of myoglianin in regulating adult performance and lifespan

    Augustin, H., Adcott, J., Elliott, C. J. H. & Partridge, L., 1 Oct 2017

    Article in Fly

  30. A spatial interactome reveals the protein organization of the algal CO2 concentrating mechanism

    Mackinder, L., Chen, C., Leib, R., Patena, W., Blum, S. R., Rodman, M., Ramundo, S., Adams, C. M. & Jonikas, M. C., 21 Sep 2017

    Article in Cell

  31. The eukaryotic CO2-concentrating organelle is liquid-like and exhibits dynamic reorganization

    Rosenzweig, E. S. F., Xu, B., Cuellar, L. K., Martinez-Sanchez, A., Schaffer, M., Strauss, M., Cartwright, H. N., Ronceray, P., Plitzko, J. M., Foster, F., Wingreen, N. S., Engel, B. E., Mackinder, L. C. M. & Jonikas, M. C., 21 Sep 2017

    Article in Cell

  32. Conformational heterogeneity in a fully-complementary DNA three-way junction with a GC-rich branchpoint

    Toulmin, A., Baltierra-Jasso, L. E., Morten, M. J., Sabir, T., McGlynn, P., Schroeder, G. F., Smith, B. O. & Magennis, S. W., 19 Sep 2017

    Article in Biochemistry

  33. Can collective memories shape fish distributions? A test, linking space-time occurrence models and population demographics

    MacDonald, J., Logemann, K., Krainski, E., Sigurdsson, P., Beale, C. M., Huse, G., Hjollo, S. & Marteinsdottir, G., 13 Sep 2017

    Article in Ecography

  34. Potential for energy production from farm wastes using anaerobic digestion in the UK: An economic comparison of different size plants

    Oreggioni, G. D., Gowreesunker, B. L., Tassou, S. A., Bianchi, G., Reilly, M., Kirby, M. E., Toop, T. A. & Theodorou, M. K., 13 Sep 2017

    Article in Energies

  35. Targeting deficiencies in the TLR5 mediated vaginal response to treat female recurrent urinary tract infection

    Ali, A. SM., Mowbray, C., Lanz, M., Stanton, A., Bowen, S., Varley, C. L., Hilton, P., Brown, K., Robson, W., Southgate, J., Aldridge, P., Tyson-Capper, A., Abraham, S., Pickard, R. & Hall, J., 8 Sep 2017

    Article in Scientific Reports

  36. A DiCre recombinase-based system for inducible expression in Leishmania major

    Santos, R. E. R. S., Silva, G. L. A., Santos, E. V., Duncan, S. M., Mottram, J. C., Damasceno, J. D. & Tosi, L. R. O., 1 Sep 2017

    Article in MOLECULAR AND BIOCHEMICAL PARASITOLOGY

  37. A national-scale assessment of climate change impacts on species: assessing the balance of risks and opportunities for multiple taxa

    Pearce-Higgins, J. W., Beale, C. M., Oliver, T., August, T., Carroll, M. J., Massimino, D., Ockendon, N., Savage, J., Wheatley, C. J., Ausden, M., Bradbury, R. B., Duffield, S., Macgregor, N., McClean, C. J., Morecroft, M. D., Thomas, C., Watts, O., Beckmann, B., Fox, R., Roy, H. E. & 3 others, Sutton, P., Walker, K. & Crick, H. Q. P., 1 Sep 2017

    Article in Biological Conservation

  38. Architecture and dynamics of the jasmonic acid gene regulatory network

    Hickman, R., Van Verk, M. C., Van Dijken, A. J. H., Pereira Mendes, M., Vroegop-Vos, I. A., Caarls, L., Steenbergen, M., Van der Nagel, I., Wesselink, G. J., Jironkin, A., Talbot, A., Rhodes, J., De Vries, M., Schuurink, R. C., Denby, K., Pieterse, C. M. J. & Van Wees, S. CM., 1 Sep 2017

    Article in The Plant Cell

  39. Investigating the structural compaction of biomolecules upon transition to the gas-phase using ESI-TWIMS-MS

    Devine, P. W. A., Fisher, H. C., Calabrese, A. N., Whelan, F., Higazi, D. R., Potts, J. R., Lowe, D. C., Radford, S. E. & Ashcroft, A. E., 1 Sep 2017

    Article in JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

  40. Transcription factor clusters regulate genes in eukaryotic cells

    Wollman, A., Shashkova, S., Hedlund, E. G., Friemann, R., Hohmann, S. & Leake, M. C., 25 Aug 2017

    Article in eLife

  41. Control of serine integrase recombination directionality by fusion with the directionality factor

    Olorunniji, F. J., McPherson, A. L., Rosser, S. J., Smith, M. C. M., Colloms, S. D. & Stark, W. M., 21 Aug 2017

    Article in Nucleic Acids Research

  42. Flexible silicon-based alpha-particle detector

    Schuster, C. S., Smith, B. R., Sanderson, B. J., Mullins, J. T., Atkins, J., Joshi, P., McNamara, L., Krauss, T. F. & Jenkins, D. G., 16 Aug 2017

    Article in Applied Physics Letters

  43. Retuning the Catalytic Bias and Overpotential of a [NiFe]-Hydrogenase via a Single Amino Acid Exchange at the Electron Entry/Exit Site

    Adamson, H., Robinson, M., Wright, J. J., Flanagan, L. A., Walton, J., Elton, D. M., Gavaghan, D. J., Bond, A. M., Roessler, M. M. & Parkin, A., 9 Aug 2017

    Article in Journal of the American Chemical Society

  44. Imaging the cell

    Carrascosa, J. L. & Leake, M. C., 3 Aug 2017

    Article in Biophysical Reviews

  45. Local factors mediate the response of biodiversity to land use on two African mountains

    Jung, M., Hill, S. L. L., Platts, P. J., Marchant, R., Siebert, S., Fournier, A., Munyekenye, F. B., Purvis, A., Burgess, N. D. & Newbold, T., 1 Aug 2017

    Article in Animal Conservation

  46. Overexpression of Arabidopsis FLOWERING LOCUS T (FT) gene improves floral development in cassava (Manihot esculenta, Crantz)

    Adeyemo, O. S., Chavarriaga, P., Tohme, J., Fregene, M., Davis, S. J. & Setter, T. L., 28 Jul 2017

    Article in PLoS ONE

  47. Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei

    Stortz, J. A., Serafim, T. D., Alsford, S., Wilkes, J., Fernandez-Cortes, F., Hamilton, G., Briggs, E., Lemgruber, L., Horn, D., Mottram, J. C. & McCulloch, R., 24 Jul 2017

    Article in PLOS PATHOGENS

  48. RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse

    Fernandez-Cortes, F., Serafim, T. D., Wilkes, J. M., Jones, N. G., Ritchie, R., McCulloch, R. & Mottram, J. C., 21 Jul 2017

    Article in Scientific Reports

  49. Historical biome distribution and recent human disturbance shape the diversity of arbuscular mycorrhizal fungi

    Partel, M., Öpik, M., Tedersoo, L., Szava-Kovats, R., Rosendahl, S., Rillig, M. C., Lekberg, Y., Kreft, H., Helgason, T., Eriksson, O., Davison, J., de Bello, F., Caruso, T., Zobel, M. & Moora, M., 19 Jul 2017

    Article in New Phytologist

  50. Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades

    Gaudry, M. J., Jastroch, M., Treberg, J. R., Hofreiter, M., Paijmans, J. L. A., Starrett, J., Wales, N., Signore, A. V., Springer, M. S. & Campbell, K. L., 12 Jul 2017

    Article in Science Advances

  51. Continent-level drivers of African pyrodiversity

    Hempson, G. J., Parr, C. L., Archibald, S., Anderson, T. M., Courtney-Mustaphi, C. J., Dobson, A. P., Donaldson, J. E., Morrison, T. A., Probert, J., Beale, C. M. & Anderson, T. M., 11 Jul 2017

    Article in Ecography

  52. Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins

    Bridge, K. S., Shah, K. M., Li, Y., Foxler, D. E., Wong, S. C. K., Miller, D. C., Davidson, K. M., Foster, J. G., Rose, R., Hodgkinson, M. R., Ribeiro, P. S., Aboobaker, A. A., Yashiro, K., Wang, X., Graves, P. R., Plevin, M. J., Lagos, D. & Sharp, T. V., 5 Jul 2017

    Article in Cell reports

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