Search research publications and outputs

  1. Article › Research › Peer-reviewed
  2. A HIF-LIMD1 negative feedback mechanism drives the adaptive response to hypoxia and mitigates pro-tumorigenic hypoxic effects

    Bridge, K., Foxler, D. E., Foster, J. G., Grevitt, P., Curry, S., Shah, K. M., Davidson, K. M., Nagano, A., Gadaleta, E., Rhys, H. I., Kennedy, P. T., Hermida, M. A., Chang, T-Y., Shaw, P. E., Reynolds, L. E., McKay, T. R., Wang, H-W., Ribeiro, P. S., Plevin, M. J., Lagos, D. & 7 others, Lemoine, N. R., Rajan, P., Graham, T. A., Chelala, C., Hodivala-Dilke, K. M., Spendlove, I. & Sharp, T. V., 1 Jul 2018

    Article in EMBO Molecular Medicine

  3. A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis

    Mottram, J. C., Jeffares, D., Brambilla Carnielli Trindade, J., Crouch, K., Forrester, S. J., Costa Silva, V., Carvalho, S. F. G., Damasceno, J. D., Brown, E., Dickens, N. J., Costa, D. L., Costa, C. H. N. & Dietze, R., 27 Sep 2018

    Article in EBioMedicine

  4. A comparison of satellite remote sensing data fusion methods to map peat swamp forest loss in Sumatra, Indonesia

    Crowson, M., Warren-Thomas, E. M., Hill, J. K., Hariyadi, B., Agus, F., Saad, A., Hamer, K. C., Hodgson, J. A., Kartika, W. D., Lucey, J. M., McClean, C. J., Nurida, N. L., Pratiwi, E., Stringer, L. C., Ward, C. F. M. & Pettorelli, N., 10 Dec 2018

    Article in Remote Sensing in Ecology and Conservation

  5. A glycosyl transferase family 43 protein involved in xylan biosynthesis is associated with straw digestibility in Brachypodium distachyon

    Whitehead, C., Ostos Garrido, F. J., Reymond, M., Simister, R., Distelfeld, A., Atienza, S. G., Piston, F., Gomez, L. D. & Mcqueen-Mason, S. J., 25 Mar 2018

    Article in The New phytologist

  6. A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes

    Papachristou, EK., Kishore, K., Holding, AN., Harvey, K., Roumeliotis, TI., Chilamakuri, CSR., Omarjee, S., Chia, KM., Swarbrick, A., Lim, E., Markowetz, F., Eldridge, M., Siersbaek, R., D'Santos, CS. & Carroll, JS., 13 Jun 2018

    Article in Nature Communications

  7. ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function

    de Majo, M., Topp, S. D., Smith, B. N., Nishimura, A. L., Chen, H-J., Soragia-Gkazi, A., Miller, J., Wong, C. H., Vance, C., Baas, F., ten Asbroek, A. LMA., Kenna, K. P., Ticozzi, N., Redondo, A. G., Esteban-Pérez, J., Tiloca, C., Verde, F., Duga, S., Morrison, K. E., Shaw, P. J. & 13 others, Kirby, J., Turner, M. R., Talbot, K., Hardiman, O., Glass, J. D., de Belleroche, J., Gellera, C., Ratti, A., Al-Chalabi, A., Brown Jr., R. H., Silani, V., Landers, J. E. & Shaw, C. E., 25 Jun 2018

    Article in Neurobiology of Aging

  8. Alpha-v-containing integrins are host receptors for the Plasmodium falciparum sporozoite surface protein, TRAP.

    Dundas, K., Shears, M. J., Sun, Y., Hopp, C. S., Crosnier, C., Metcalf, T., Girling, G., Sinnis, P., Billker, O. & Wright, G. J., 24 Apr 2018

    Article in Proceedings of the National Academy of Sciences USA

  9. An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness

    Galarza Torre, A., Shaw, J. E., Wood, A., Gilbert, H. T. J., Dobre, O., Genever, P. G., Brennan, K., Richardson, S. M. & Swift, J., 12 Jun 2018

    Article in Scientific Reports

  10. Analyses of ovarian activity reveal repeated evolution of post-reproductive lifespans in toothed whales

    Ellis, S., Franks, D. W., Nattrass, S., Currie, T., Cant, M. A., Giles, D., Balcomb, K. C. & Croft, D. P., 27 Aug 2018

    Article in Scientific Reports

  11. Annual cycles are the most common reproductive strategy in African tropical tree communities

    Adamescu, G. S., Plumptre, A. J., Abernethy, K. A., Polansky, L., Bush, E. R., Chapman, C. A., Shoo, L. P., Fayolle, A., Janmaat, K. R. L., Robbins, M. M., Ndangalasi, H. J., Cordeiro, N. J., Gilby, I. C., Wittig, R. M., Breuer, T., Ndoundou-Hockemba, M., Sanz, C. M., Morgan, D. B., Pusey, A. E., Mugerwa, B. & 19 others, Gilagiza, B., Tutin, C., Ewango, C. E. N., Sheil, D., Dimoto, E., Baya, F., Bujo, F., Ssali, F., Dikangadissi, J. T., Jeffery, K. J., Valenta, K., White, L. J. T., Masozera, M., Wilson, M. L., Bitariho, R., Ndolo Ebika, S. T., Gourlet-Fleury, S., Mulindahabi, F. & Beale, C. M., 16 May 2018

    Article in Biotropica

  12. Be 7 (n,p) Li 7 Reaction and the Cosmological Lithium Problem: Measurement of the Cross Section in a Wide Energy Range at n-TOF at CERN

    Damone, L., Barbagallo, M., Mastromarco, M., Mengoni, A., Cosentino, L., Maugeri, E., Heinitz, S., Schumann, D., Dressler, R., Käppeler, F., Colonna, N., Finocchiaro, P., Andrzejewski, J., Perkowski, J., Gawlik, A., Aberle, O., Altstadt, S., Ayranov, M., Audouin, L., Bacak, M. & 31 others, Balibrea-Correa, J., Ballof, J., Bécares, V., Bečvář, F., Beinrucker, C., Bellia, G., Bernardes, A. P., Berthoumieux, E., Billowes, J., Borge, M. J. G., Bosnar, D., Brown, A., Brugger, M., Busso, M., Caamaño, M., Calviño, F., Calviani, M., Cano-Ott, D., Cardella, R., Casanovas, A., Castelluccio, D. M., Catherall, R., Cerutti, F., Chen, Y. H., Chiaveri, E., Correia, J. G. M., Cortés, G., Cortés-Giraldo, M. A., Jenkins, D. G., Wright, T. & (The n-TOF Collaboration [www.cern.ch/ntof]), 24 Jul 2018

    Article in Physical Review Letters

  13. Bringing numerous methods for expression and promoter analysis to a public cloud computing service

    Polanski, K., Gao, B., Mason, S. A., Brown, P., Ott, S., Denby, K. & Wild, D. L., 1 Mar 2018

    Article in Bioinformatics

  14. CXCL4/Platelet Factor 4 is an agonist of CCR1 and drives human monocyte migration

    Fox, J. M., Kausar, F., Day, A., Osborne, M., Hussain, K., Mueller, A., Lin, J., Tsuchiya, T., Kanegasaki, S. & Pease, J., 21 Jun 2018

    Article in Scientific Reports

  15. Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides

    Waszkowycz, B., Smith, K. M., McGonagle, A. E., Jordan, A. M., Acton, B., Fairweather, E. E., Griffiths, L. A., Hamilton, N. M., Hamilton, N. S., Hitchin, J. R., Hutton, C. P., James, D. I., Jones, C. D., Jones, S., Mould, D. P., Small, H. F., Stowell, A. I. J., Tucker, J. A., Waddell, I. D. & Ogilvie, D. J., 13 Dec 2018

    Article in JOURNAL OF MEDICINAL CHEMISTRY

  16. Circadian rhythms are associated with shoot architecture in natural settings.

    Rubin, M., Brock, M., Baker, R. L., Wilcox, S., Anderson, K., Davis, S. J. & Weinig, C., 1 Jul 2018

    Article in New Phytologist

  17. Conditional genome engineering reveals canonical and divergent roles for the Hus1 component of the 9-1-1 complex in the maintenance of the plastic genome of Leishmania.

    Damasceno, J. D., Obonaga, R., Silva, G. L. A., Reis-Cunha, J. L., Duncan, S. M., Bartholomeu, D. C., Mottram, J. C., McCulloch, R. & Tosi, L. R. O., 14 Dec 2018

    Article in Nucleic Acids Research

  18. Coordinated regulation of core and accessory genes in the multipartite genome of Sinorhizobium fredii

    Jiao, J., Ni, M., Zhang, B., Zhang, Z., Young, J. P. W., Chan, T-F., Chen, W. X., Lam, H-M. & Tian, C. F., 24 May 2018

    Article in PLoS Genetics

  19. Cryptic dispersal of Cyanidiophytina (Rhodophyta) in non-acidic environments from Turkey

    Iovinella, M., Eren, A., Pinto, G., Pollio, A., Davis, S. J., Cennamo, P. & Ciniglia, C., 1 Sep 2018

    Article in Extremophiles

  20. Cryptic speciation associated with geographic and ecological divergence in two Amazonian Heliconius butterflies

    Rosser, N. S., Freitas, A., Huertas, B., Joron, M., Lamas, G., Merot, C., Simpson, F., Willmott, K. R., Mallet, J. & Dasmahapatra, K. K., 4 Aug 2018

    Article in Zoological journal of the linnean society

  21. Differential transcription factor expression by human epithelial cells of buccal and urothelial derivation

    Southgate, J., Hustler, A., Eardley, I., Hinley, J. S., Pearson, J. F., Wezel, F., Radvanyi, F. & Baker, S. C., 15 Aug 2018

    Article in Experimental cell research

  22. Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolising activity of “luminal” muscle-invasive bladder cancers

    Baker, S. C., Arlt, V., Indra, R., Joel, M., Stiborova, M., Eardley, I., Ahmad, N., Otto, W., Burger, M., Rubenwolf, P. C., Phillips, D. & Southgate, J., 1 May 2018

    Article in Molecular Carcinogenesis

  23. Dissecting the complex regulation of lodging resistance in Brassica napus

    Miller, C. N., Harper, A. L., Trick, M., Wellner, K., Peter, W., Waldron, K. & Bancroft, I., 1 Mar 2018

    Article in Molecular Breeding

  24. Drug Discovery for Kinetoplastid Diseases: Future Directions

    Rao, S. P. S., Barrett, M., Dranoff, G., Faraday, C., Gimpelewicz, C. R., Hailu, A., Jones, C. L., Kelly, J. M., Lazdins-Helds, J. K., Maeser, P., Mengel, J., Mottram, J. C., Mowbray, C. E., Sacks, D. L., Scott, P., Spath, G. F., Tarleton, R. L., Spector, J. M. & Diagana, T. T., 13 Dec 2018

    Article in ACS Infectious Diseases

  25. Dryland management regimes alter forest habitats and understory arthropod communities

    Johnson, S. N., Lopaticki, G., Aslam, T. J., Barnett, K., Frew, A., Hartley, S. E., Hiltpold, I., Nielsen, U. N. & Ryalls, J. M. W., 1 May 2018

    Article in Annals of applied biology

  26. EMP control and characterization on high-power laser systems

    Bradford, P., Woolsey, N. C., Scott, G. G., Liao, G., Liu, H., Zhang, Y., Zhu, B., Armstrong, C., Astbury, S., Brenner, C. & al., E., 21 May 2018

    Article in High Power Laser Science and Engineering

  27. Effects of microcompartmentation on flux distribution and metabolic pools in Chlamydomonas reinhardtii chloroplasts

    Kuken, A., Sommer, F., Yaneva-Roder, L., Mackinder, L., Hohne, M., Geimer, S., Jonikas, M. C., Schroda, M., Stitt, M., Nikoloski, Z. & Mettler-Altmann, T., 11 Oct 2018

    Article in eLife

  28. Enteral lactoferrin to prevent infection for very preterm infants: the ELFIN RCT

    Griffiths, J., Jenkins, P., Vargova, M., Bowler, U., Juszczak, E., King, A., Linsell, L., Murray, D., Partlett, C., Patel, M., Berrington, J., Embleton, N., Dorling, J., Heath, P. T., McGuire, W. & Oddie, S., 20 Dec 2018

    Article in Health technology assessment

  29. Evolution of Genome Architecture in Archaea: Spontaneous Generation of a New Chromosome in Haloferax volcanii

    Ausiannikava, D., Mitchell, L., Marriott, H., Smith, V., Hawkins, M., Makarova, K. S., Koonin, E. V., Nieduszynski, C. A. & Allers, T., Aug 2018

    Article in Molecular Biology and Evolution

  30. Extinction risk from climate change is reduced by microclimatic buffering

    Suggitt, A., Wilson, R. J., Isaac, N. J. B., Beale, C. M., Auffret, A. G., August, T., Bennie, J. J., Crick, H. Q. P., Duffield, S., Fox, R., Hopkins, J. J., Macgregor, N., Morecroft, M. D., Walker, K. J. & Maclean, I. M. D., 23 Jul 2018

    Article in Nature Climate Change

  31. First Measurement of 72Ge(n, γ) at n-TOF

    Dietz, M., Lederer-Woods, C., Aberle, O., Andrzejewski, J., Audouin, L., Bacak, M., Balibrea, J., Barbagallo, M., Bečvář, F., Berthoumieux, E., Billowes, J., Bosnar, D., Brown, A., Caamaño, M., Calviño, F., Calviani, M., Cano-Ott, D., Cardella, R., Casanovas, A., Cerutti, F. & 101 others, Chen, Y. H., Chiaveri, E., Colonna, N., Cortés, G., Cortés-Giraldo, M. A., Cosentino, L., Damone, L. A., Diakaki, M., Domingo-Pardo, C., Dressler, R., Dupont, E., Durán, I., Fernández-Domínguez, B., Ferrari, A., Ferreira, P., Finocchiaro, P., Furman, V., Göbel, K., García, A. R., Garg, R., Gawlik, A., Gilardoni, S., Glodariu, T., Gonçalves, I. F., González-Romero, E., Griesmayer, E., Guerrero, C., Gunsing, F., Harada, H., Heinitz, S., Heyse, J., Jenkins, D. G., Jericha, E., Käppeler, F., Kadi, Y., Kahl, D., Kalamara, A., Kavrigin, P., Kimura, A., Kivel, N., Kokkoris, M., Krtička, M., Kurtulgil, D., Leal-Cidoncha, E., Leeb, H., Lerendegui-Marco, J., Lo Meo, S., Lonsdale, S. J., Macina, D., Marganiec, J., Martínez, T., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Maugeri, E. A., Mazzone, A., Mendoza, E., Mengoni, A., Milazzo, P. M., Mingrone, F., Musumarra, A., Negret, A., Nolte, R., Oprea, A., Patronis, N., Pavlik, A., Perkowski, J., Porras, I., Praena, J., Quesada, J. M., Radeck, D., Rauscher, T., Reifarth, R., Rubbia, C., Ryan, J. A., Sabaté-Gilarte, M., Saxena, A., Schillebeeckx, P., Schumann, D., Sedyshev, P., Smith, A. G., Sosnin, N. V., Stamatopoulos, A., Tagliente, G., Tain, J. L., Tarifeño-Saldivia, A., Tassan-Got, L., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vlachoudis, V., Vlastou, R., Wallner, A., Warren, S., Weiss, C., Woods, P. J., Wright, T. & Žugec, P., 29 Jun 2018

    Article in EPJ Web of Conferences

  32. Functional and informatics analysis enables glycosyltransferase activity prediction

    Yang, M., Fehl, C., Lees, K. V., Lim, E-K., Offen, W. A., Davies, G. J., Bowles, D. J., Davidson, M. G., Roberts, S. J. & Davis, B. G., 12 Nov 2018

    Article in NATURE CHEMICAL BIOLOGY

  33. Gamma decay of pygmy states in 90,94Zr from inelastic scattering of light ions

    Crespi, F. C. L., Bracco, A., Tamii, A., Blasi, N., Camera, F., Wieland, O., Aoi, N., Balabanski, D., Bassauer, S., Brown, A. S., Carpenter, M. P., Carroll, J. J., Ciemala, M., Czeszumska, A., Davies, P. J., Donaldson, L., Fang, Y., Fujita, H., Gey, G., Hoang, T. H. & 28 others, Ichige, N., Ideguchi, E., Inoue, A., Isaak, J., Iwamoto, C., Jenkins, D. G., Jin, O. H., Klaus, T., Kobayashi, N., Koike, T., Krzysiek, M., Kumar Raju, M., Liu, M., Maj, A., Montanari, D., Morris, L., Noji, S., Pickstone, S. G., Savran, D., Spieker, M., Steinhilber, G., Sullivan, C., Wasilewska, B., Werner, V., Yamamoto, T., Yamamoto, Y., Zhou, X. & Zhu, S., 10 May 2018

    Article in Journal of Physics: Conference Series

  34. Genome-scale identification of cellular pathways required for cell surface recognition.

    Sharma, S., Bartholdson, S. J., Couch, A. C. M., Yusa, K. & Wright, G. J., Sep 2018

    Article in Genome Research

  35. Global Assessment of Agricultural System Redesign for Sustainable Intensification

    Pretty, J., Benton, T. G., Bharucha, Z. P., Dicks, L. V., Flora, C. B., Godfray, H. C. J., Goulson, D., Hartley, S. E., Lampkin, N., Morris, C., Pierzynski, G., Vara Prasad, P. V., Reganold, J., Rockstrom, J., Smith, P., Thorne, P. & Wratten, S., 14 Aug 2018

    Article in Nature Sustainability

  36. Hemocyanin facilitates lignocellulose digestion by wood-boring marine crustaceans

    Besser, K., Malyon, G. P., Eborall, W. S., Paro da Cunha, G., Goncalves Filgueiras, J., Dowle, A., Cruz Garcia, L., Page, S. J., Dupree, R., Kern, M. F., Gomez, L. D., Li, Y., Elias, L., Sabbadin, F., Mohamad, S. E., Pesante, G., Steele-King, C. G., Ribeiro de Azevedo, E., Polikarpov, I., Dupree, P. & 3 others, Cragg, S. M., Bruce, N. C. & McQueen Mason, S. J., 3 Dec 2018

    Article in Nature Communications

  37. Horizontal Transfer of Symbiosis Genes within and Between Rhizobial Genera: Occurrence and Importance

    Andrews, M., Meyer, S., James, E. K., Stępkowski, T., Hodge, S., Simon, M. F. & Young, J. P. W., 27 Jun 2018

    Article in Genes

  38. Identification of iridoid synthases from Nepeta species: Iridoid cyclization does not determine nepetalactone stereochemistry

    Sherden, N. H., Lichman, B., Caputi, L., Zhao, D., Kamileen, M. O., Buell, C. R. & O'Connor, S. E., 1 Jan 2018

    Article in PHYTOCHEMISTRY

  39. Improving chronological control for environmental sequences from the last glacial period

    Briant, R. M., Brock, F., Demarchi, B., Langford, H. E., Penkman, K. E. H., Schreve, D. C., Schwenninger, J-L. & Taylor, S., 1 Feb 2018

    Article in Quaternary Geochronology

  40. Improving the effectiveness of psychological interventions for depression and anxiety in the cardiac rehabilitation pathway using group-based metacognitive therapy (PATHWAY Group MCT): study protocol for a randomised controlled trial

    Wells, A., McNicol, K., Reeves, D., Salmon, P., Davies, L., Heagerty, A., Doherty, P., McPhillips, R., Anderson, R., Faija, C., Capobianco, L., Morley, H., Gaffney, H., Shields, G. & Fisher, P., 3 Apr 2018

    Article in Trials

  41. Incipient signs of genetic differentiation among African elephant populations in fragmenting miombo ecosystems in south-western Tanzania

    Lobora, A. L., Nahonyo, C. L., Munishi, L. K., Caro, T., Foley, C., Prunier, J. G., Beale, C. M. & Eggert, L. S., 1 Dec 2018

    Article in African Journal of Ecology

  42. Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion

    Monteleone, M., Stanley, A. C., Chen, K. W., Brown, D. L., Bezbradica, J. S., von Pein, J. B., Holley, C. L., Boucher, D., Shakespear, M. R., Kapetanovic, R., Rolfes, V., Sweet, M. J., Stow, J. L. & Schroder, K., 7 Aug 2018

    Article in Cell reports

  43. Intermembrane crosstalk drives inner membrane protein organization in Escherichia coli

    Rassam, P., Long, K. R., Kaminska, R., Williams, D. J., Papadakos, G., Baumann, C. G. & Kleanthous, K., 14 Mar 2018

    Article in Nature Communications

  44. Isoprostanoids quantitative profiling of marine red and brown macroalgae

    Vigor, C., Reversat, G., Rocher, A., Oger, C., Galano, J-M., Vercauteren, J., Durand, T., Tonon, T., Leblanc, C. & Potin, P., 1 Dec 2018

    Article in Food Chemistry

  45. KIN7 kinase regulates the vacuolar TPK1 K+ channel during stomatal closure

    Isner, J-C. E. F., Begum, A., Nuehse, T., Hetherington, A. M. & Maathuis, F. J. M., 5 Feb 2018

    Article in Current Biology

  46. Leishmania genome dynamics during environmental adaptation reveals strain-specific differences in gene copy number variation, karyotype instability, and telomeric amplification

    Bussotti, G., Gouzelou, E., Cortes Boite, M., Kherachi, I., Harrat, Z., Eddaikra, N., Mottram, J. C., Antoniou, M., Christodoulou, V., Bali, A., Guerfali, F. Z., Laouini, D., Mukhtar, M., Dumetz, F., Dujardin, J-C., Smirlis, D., Lechat, P., Pescher, P., El Hamouchi, A., Lemrani, M. & 10 others, Chicharro, C., Llanes-Acevedo, I. P., Botana, L., Cruz, I., Moreno, J., Jeddi, F., Aoun, K., Bouratbine, A., Cupolillo, E. & Spath, G. F., 6 Nov 2018

    Article in MBio

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