Search research publications and outputs

  1. Single-cell reconstruction of the early maternal-fetal interface in humans.

    Vento-Tormo, R., Efremova, M., Botting, R. A., Turco, M. Y., Vento-Tormo, M., Meyer, K. B., Park, J-E., Stephenson, E., Polański, K., Goncalves, A., Gardner, L., Holmqvist, S., Henriksson, J., Zou, A., Sharkey, A. M., Millar, B., Innes, B., Wood, L., Wilbrey-Clark, A., Payne, R. P. & 10 others, Ivarsson, M. A., Lisgo, S., Filby, A., Rowitch, D. H., Bulmer, J. N., Wright, G. J., Stubbington, M. J. T., Haniffa, M., Moffett, A. & Teichmann, S. A., 14 Nov 2018

    Article in Nature

  2. Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal.

    Shepherd, MS., Li, J., Wilson, NK., Oedekoven, CA., Li, J., Belmonte, M., Fink, J., Prick, JCM., Pask, DC., Hamilton, TL., Loeffler, D., Rao, A., Schröder, T., Göttgens, B., Green, AR. & Kent, DG., 23 Aug 2018

    Article in Blood

  3. Potential drug targets in the pentose phosphate pathway of trypanosomatids.

    Loureiro, I., Correia Faria, J. R., Santarem, N., Smith, T. K., Tavares, J. & Cordeiro-da-Silva, A., 2018

    Article in Current Medicinal Chemistry

  4. Population dynamics of normal human blood inferred from somatic mutations

    Lee-Six, H., Øbro, NF., Shepherd, MS., Grossmann, S., Dawson, K., Belmonte, M., Osborne, RJ., Huntly, BJP., Martincorena, I., Anderson, E., O'Neill, L., Stratton, MR., Laurenti, E., Green, AR., Kent, DG. & Campbell, PJ., 27 Sep 2018

    Article in Nature

  5. Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps

    Chen, K. W., Monteleone, M., Boucher, D., Sollberger, G., Ramnath, D., Condon, N. D., von Pein, J. B., Broz, P., Sweet, M. J. & Schroder, K., 24 Aug 2018

    Article in Science Immunology

  6. Niche Heterogeneity Impacts Evolution of Myeloproliferative Neoplasms Driven By the Same Oncogenic Pathway

    Korn, C., Rak, J., Garcia-Garcia, A., Fielding, C., Khorshed, R., Gonzalez-Anton, S., Li, J., Norfo, R., Baxter, EJ., McKerrell, T., Roberts, T., Eldaly, H., Godfrey, AL., Castillo-Venzor, A., Kusumbe, A., Mead, AJ., Green, AR., Kent, D., Lo Celso, C. & Mendez-Ferrer, S., 29 Nov 2018

    Article in Blood

  7. Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage.

    Li, J., Prins, D., Park, HJ., Grinfeld, J., Gonzalez-Arias, C., Loughran, S., Dovey, OM., Klampfl, T., Bennett, C., Hamilton, TL., Pask, DC., Sneade, R., Williams, M., Aungier, J., Ghevaert, C., Vassiliou, GS., Kent, DG. & Green, AR., 8 Feb 2018

    Article in Blood

  8. KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice

    Polson, ES., Kuchler, VB., Abbosh, C., Ross, EM., Mathew, RK., Beard, HA., da Silva, B., Holding, AN., Ballereau, S., Chuntharpursat-Bon, E., Williams, J., Griffiths, HBS., Shao, H., Patel, A., Davies, AJ., Droop, A., Chumas, P., Short, SC., Lorger, M., Gestwicki, JE. & 6 others, Roberts, LD., Bon, RS., Allison, SJ., Zhu, S., Markowetz, F. & Wurdak, H., 15 Aug 2018

    Article in Science Translational Medicine

  9. Identification of residues in ABCG2 affecting protein trafficking and drug transport, using co-evolutionary analysis of ABCG sequences

    Haider, A. J., Cox, M. H., Jones, N., Goode, A. J., Bridge, K. S., Wong, K., Briggs, D. & Kerr, I. D., 1 Aug 2018

    Article in Bioscience Reports

  10. Experimental setup and procedure for the measurement of the 7Be(n,p)7Li reaction at n_TOF

    Barbagallo, M., Andrzejewski, J., Mastromarco, M., Perkowski, J., Damone, L. A., Gawlik, A., Cosentino, L., Finocchiaro, P., Maugeri, E. A., Mazzone, A., Dressler, R., Heinitz, S., Kivel, N., Schumann, D., Colonna, N., Aberle, O., Amaducci, S., Audouin, L., Bacak, M., Balibrea-Correa, J. & 109 others, Bečvář, F., Bellia, G., Berthoumieux, E., Billowes, J., Bosnar, D., Brown, A., Caamaño, M., Calviño, F., Calviani, M., Cano-Ott, D., Cardella, R., Casanovas, A., Cerutti, F., Chen, Y. H., Chiaveri, E., Cortés, G., Cortés-Giraldo, M. A., Cristallo, S., Diakaki, M., Dietz, M., Domingo-Pardo, C., Dupont, E., Durán, I., Fernández-Domínguez, B., Ferrari, A. C., Ferreira, P. R., Furman, V., Göbel, K., García, A. R., Gilardoni, S., Glodariu, T., Gonçalves, I. F., González-Romero, E., Griesmayer, E., Guerrero, C., Gunsing, F., Harada, H., Heyse, J., Jenkins, D. G., Jericha, E., Johnston, K., Käppeler, F., Kadi, Y., Kalamara, A., Kavrigin, P., Kimura, A., Kokkoris, M., Krtička, M., Kurtulgil, D., Leal-Cidoncha, E., Lederer, C., Leeb, H., Lerendegui-Marco, J., Lo Meo, S., Lonsdale, S. J., Macina, D., Manna, A., Marganiec, J., Martínez, T., Martins-Correia, J. G., Masi, A., Massimi, C., Mastinu, P. F., Mendoza, E., Mengoni, A., Milazzo, P. M., Mingrone, F., Musumarra, A., Negret, A., Nolte, R., Oprea, A., Pappalardo, A. D., Patronis, N., Pavlik, A., Piscopo, M., Porras, I., Praena, J., Quesada, J. M., Radeck, D., Rauscher, T., Reifarth, R., Robles, M. S., Rubbia, C., Ryan, J. A., Sabaté-Gilarte, M., Saxena, A. K., Schell, M. J., Schillebeeckx, P., Sedyshev, P., Smith, A. G., Sosnin, N. V., Stamatopoulos, A., Tagliente, G., Tain, J. L., Tarifeño-Saldivia, A., Tassan-Got, L., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vlachoudis, V., Vlastou, R., Wallner, A., Warren, S., Weiss, C., Woods, P. J., Wright, T. & Žugec, P., 11 Apr 2018

    Article in Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

  11. Defining the requirements for the pathogenic interaction between mutant calreticulin and MPL in MPN

    Elf, S., Abdelfattah, N. S., Baral, A. J., Rivera, J., Chen, E. & Mullaly, A., 15 Feb 2018

    Article in Blood

  12. Defining and delivering resilient ecological networks: Nature conservation in England

    Isaac, N. J. B., Brotherton, P. N. M., Bullock, J. M., Gregory, R. D., Boehning-Gaese, K., Connor, B., Crick, H. Q. P., Freckleton, R. P., Gill, J. A., Hails, R. S., Hartikainen, M., Hester, A. J., Milner-Gulland, E. J., Oliver, T. H., Pearson, R. G., Sutherland, W. J., Thomas, C., Travis, J. M. J., Turnbull, L. A., Willis, K. & 2 others, Woodward, G. & Mace, G. M., 1 Nov 2018

    Article in Journal of Applied Ecology

  13. Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion

    Chen, K. W., Lawlor, K. E., von Pein, J. B., Boucher, D., Gerlic, M., Croker, B. A., Bezbradica, J. S., Vince, J. E. & Schroder, K., 15 May 2018

    Article in Journal of Immunology

  14. Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

    Boucher, D., Monteleone, M., Coll, R. C., Chen, K. W., Ross, C. M., Teo, J. L., Gomez, G. A., Holley, C. L., Bierschenk, D., Stacey, K. J., Yap, A. S., Bezbradica, J. S. & Schroder, K., 6 Feb 2018

    Article in The Journal of experimental medicine

  15. A track of the clones: new developments in cellular barcoding.

    Lyne, A-M., Kent, DG., Laurenti, E., Cornils, K., Glauche, I. & Perié, L., 1 Dec 2018

    Article in Experimental hematology

  16. A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice

    Dahlin, JS., Hamey, FK., Pijuan-Sala, B., Shepherd, M. S., Lau, WWY., Nestorowa, S., Weinreb, C., Wolock, S., Hannah, R., Diamanti, E., Kent, DG., Göttgens, B. & Wilson, NK., 24 May 2018

    Article in Blood

  17. A chitin deacetylase of Podospora anserina has two functional chitin binding domains and a unique mode of action

    Hoßbach, J., Bußwinkel, F., Kranz, A., Wattjes, J., Cord-Landwehr, S. & Moerschbacher, B. M., 1 Mar 2018

    Article in CARBOHYDRATE POLYMERS