Notch signalling is a potential resistance mechanism of progenitor cells within patient-derived prostate cultures following ROS-inducing treatments

Packer, J. R., Hirst, A. M., Droop, A. P., Adamson, R., Simms, M. S., Mann, V. M., Frame, F. M., O'Connell, D. & Maitland, N. J., 17 Sep 2019

Article in FEBS Letters

Epigenetic Control of Gene Expression in the Normal and Malignant Human Prostate: A Rapid Response Which Promotes Therapeutic Resistance

Frame, F. M. & Maitland, N. J., 17 May 2019

Review article in International Journal of Molecular Sciences

The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy

Seed, R. I., Taurozzi, A. J., Wilcock, D. J., Nappo, G., Erb, H. H. H., Read, M. L., Gurney, M., Archer, L. K., Ito, S., Rumsby, M. G., Petrie, J. L., Clayton, A., Maitland, N. J. & Collins, A. T., 26 Mar 2019

Article in Scientific Reports

Effects on prostate cancer cells of targeting RNA polymerase III

Petrie, J. L., Swan, C., Ingram, R. M., Frame, F. M., Collins, A. T., Dumay-Odelot, H., Teichmann, M., Maitland, N. J. & White, R. J., 1 Mar 2019

Article in Nucleic Acids Research

Phospholipase D inhibitors reduce human prostate cancer cell proliferation and colony formation

Noble, A. R., Maitland, N. J., Berney, D. M. & Rumsby, M. G., 1 Jan 2018

Article in British journal of cancer

Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer

Butler, D. E., Marlein, C., Walker, H. F., Frame, F. M., Mann, V. M., Simms, M. S., Davies, B. R., Collins, A. T. & Maitland, N. J., 23 May 2017

Article in Oncotarget

A detailed analysis of gene expression in human basal, luminal, and stromal cell populations from benign prostatic hyperplasia tissues and comparisons with cultured basal cells

Rane, J. K., Droop, A. P. & Maitland, N. J., 3 Apr 2017

Article in European Urology

Differential microRNA expression in epithelial cell populations from human prostate: its relevance to treatment resistance in prostate cancer

Maitland, N. J., 31 Mar 2017

Article in Translational Cancer Research

Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers

Rane, J. K., Erb, H. H., Nappo, G., Mann, V. M., Simms, M. S., Collins, A. T., Visakorpi, T. & Maitland, N. J., 21 Jun 2016

Article in Oncotarget

Cyclin A1 and P450 aromatase promote metastatic homing and growth of stem-like prostate cancer cells in the bone marrow

Miftakhova, R., Hedblom, A., Semenas, J., Robinson, B. D., Simoulis, A., Malm, J., Rizvanov, A., David Heery, D., Mongan, N. P., Maitland, N. J., Allegrucci, C. & Persson, J. L., 15 Apr 2016

Article in Cancer research

An epigenetic reprogramming strategy to re-sensitize radioresistant prostate cancer cells

Peitzsch, C., Cojoc, M., Hein, L., Kurth, I., Mӓbert, K., Trautmann, F., Klink, B., Schrock, E., Wirth, M. P., Krause, M., Stakhovsky, E. A., Telegeev, G. D., Novotny, V., Toma, M. I., Muders, M., Baretton, G. B., Frame, F. M., Maitland, N. J., Baumann, M. & Dubrovska, A., 16 Mar 2016

Article in Cancer research

Low temperature plasmas as emerging cancer therapeutics: the state of play and thoughts for the future

Hirst, A. M., Frame, F. M., Arya, M., Maitland, N. J. & O'Connell, D., 2016

Article in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Low Temperature Plasma: A Novel Focal Therapy for Localized Prostate Cancer?

Hirst, A. M., Frame, F. M., Maitland, N. J. & O'Connell, D., 13 Mar 2014

Article in BioMed Research International