Selective detection of hyperpolarized NMR signals derived from para-hydrogen using the Only Para-hydrogen SpectroscopY (OPSY) approach

Juan A. Aguilar; Ralph W. Adams; Simon B. Duckett; Gary George Reginald Green; Rathika Kandiah

doi:10.1016/j.jmr.2010.10.002

Selective detection of hyperpolarized NMR signals derived from para-hydrogen using the Only Para-hydrogen SpectroscopY (OPSY) approach

Juan A. Aguilar, Ralph W. Adams, Simon B. Duckett, Gary George Reginald Green, Rathika Kandiah

Research output: Contribution to journal › Article › peer-review

Abstract

A new family of NMR pulse sequences is reported for the recording of para-hydrogen enhanced NMR spectra. This Only Para-hydrogen Spectroscopy (OPSY) approach uses coherence selection to separate hyperpolarized signals from those of fully relaxed and thermally equilibrated protons. Sequence design, performance, practical aspects and applicability to other hyperpolarization techniques are discussed. (C) 2010 Elsevier Inc. All rights reserved.

Original language	English
Pages (from-to)	49-57
Number of pages	9
Journal	Journal of Magnetic Resonance
Volume	208
Issue number	1
DOIs	https://doi.org/10.1016/j.jmr.2010.10.002
Publication status	Published - Jan 2011

Keywords

para-hydrogen
Double quantum (DQ)
Zero quantum (ZQ)
Multiple quantum
Pulsed field gradients
Coherence order selection
Signal Amplification By Reversible Exchange (SABRE)
Solvent suppression
Hyperpolarization
Hydrogenation
PARAHYDROGEN-INDUCED POLARIZATION
DYNAMIC NUCLEAR-POLARIZATION
PULSED-FIELD GRADIENTS
SITU PHIP-NMR
IN-SITU
HOMOGENEOUS HYDROGENATION
CATALYTIC-HYDROGENATION
C-13
ORDER
ACID

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10.1016/j.jmr.2010.10.002

http://www.sciencedirect.com/science/article/pii/S1090780710003022

Cite this

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title = "Selective detection of hyperpolarized NMR signals derived from para-hydrogen using the Only Para-hydrogen SpectroscopY (OPSY) approach",

abstract = "A new family of NMR pulse sequences is reported for the recording of para-hydrogen enhanced NMR spectra. This Only Para-hydrogen Spectroscopy (OPSY) approach uses coherence selection to separate hyperpolarized signals from those of fully relaxed and thermally equilibrated protons. Sequence design, performance, practical aspects and applicability to other hyperpolarization techniques are discussed. (C) 2010 Elsevier Inc. All rights reserved.",

keywords = "para-hydrogen, Double quantum (DQ), Zero quantum (ZQ), Multiple quantum, Pulsed field gradients, Coherence order selection, Signal Amplification By Reversible Exchange (SABRE), Solvent suppression, Hyperpolarization, Hydrogenation, PARAHYDROGEN-INDUCED POLARIZATION, DYNAMIC NUCLEAR-POLARIZATION, PULSED-FIELD GRADIENTS, SITU PHIP-NMR, IN-SITU, HOMOGENEOUS HYDROGENATION, CATALYTIC-HYDROGENATION, C-13, ORDER, ACID",

author = "Aguilar, {Juan A.} and Adams, {Ralph W.} and Duckett, {Simon B.} and Green, {Gary George Reginald} and Rathika Kandiah",

year = "2011",

month = jan,

doi = "10.1016/j.jmr.2010.10.002",

language = "English",

volume = "208",

pages = "49--57",

journal = "Journal of Magnetic Resonance",

issn = "1090-7807",

publisher = "Academic Press",

number = "1",

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AU - Aguilar, Juan A.

AU - Adams, Ralph W.

AU - Duckett, Simon B.

AU - Green, Gary George Reginald

AU - Kandiah, Rathika

PY - 2011/1

Y1 - 2011/1

N2 - A new family of NMR pulse sequences is reported for the recording of para-hydrogen enhanced NMR spectra. This Only Para-hydrogen Spectroscopy (OPSY) approach uses coherence selection to separate hyperpolarized signals from those of fully relaxed and thermally equilibrated protons. Sequence design, performance, practical aspects and applicability to other hyperpolarization techniques are discussed. (C) 2010 Elsevier Inc. All rights reserved.

AB - A new family of NMR pulse sequences is reported for the recording of para-hydrogen enhanced NMR spectra. This Only Para-hydrogen Spectroscopy (OPSY) approach uses coherence selection to separate hyperpolarized signals from those of fully relaxed and thermally equilibrated protons. Sequence design, performance, practical aspects and applicability to other hyperpolarization techniques are discussed. (C) 2010 Elsevier Inc. All rights reserved.

KW - para-hydrogen

KW - Double quantum (DQ)

KW - Zero quantum (ZQ)

KW - Multiple quantum

KW - Pulsed field gradients

KW - Coherence order selection

KW - Signal Amplification By Reversible Exchange (SABRE)

KW - Solvent suppression

KW - Hyperpolarization

KW - Hydrogenation

KW - PARAHYDROGEN-INDUCED POLARIZATION

KW - DYNAMIC NUCLEAR-POLARIZATION

KW - PULSED-FIELD GRADIENTS

KW - SITU PHIP-NMR

KW - IN-SITU

KW - HOMOGENEOUS HYDROGENATION

KW - CATALYTIC-HYDROGENATION

KW - C-13

KW - ORDER

KW - ACID

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U2 - 10.1016/j.jmr.2010.10.002

DO - 10.1016/j.jmr.2010.10.002

M3 - Article

SN - 1090-7807

VL - 208

SP - 49

EP - 57

JO - Journal of Magnetic Resonance

JF - Journal of Magnetic Resonance

IS - 1

ER -

Selective detection of hyperpolarized NMR signals derived from para-hydrogen using the Only Para-hydrogen SpectroscopY (OPSY) approach

Abstract

Keywords

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Basic Technology: Hyperpolarised technologies for medical and materials sciences

Cite this

Selective detection of hyperpolarized NMR signals derived from para-hydrogen using the Only Para-hydrogen SpectroscopY (OPSY) approach

Abstract

Keywords

Access to Document

Other files and links

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Euromar

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Basic Technology: Hyperpolarised technologies for medical and materials sciences

Cite this