Selective Synthesis of Six Products from a Single Indolyl α-Diazocarbonyl Precursor

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Indolyl α-diazocarbonyls can be selectively cyclized to give six distinct products through the careful choice of catalyst and reaction conditions. A range of catalysts were used, including complexes of Rh(II) , Pd(II) , and Cu(II) , as well as SiO2 , to promote diazo decomposition and subsequent cyclization/rearrangement through a range of mechanistic pathways.

Original languageEnglish
Pages (from-to)9671-9675
Number of pages5
JournalAngewandte Chemie International Edition
Issue number33
Early online date20 Jul 2016
Publication statusPublished - 8 Aug 2016

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  • cyclizations
  • diazo compounds
  • indoles
  • spirocycles
  • synthetic methods

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