Self-assembled sorbitol-derived supramolecular hydrogels for the controlled encapsulation and release of active pharmaceutical ingredients

Edward J. Howe; Babatunde O. Okesola; David K. Smith

doi:10.1039/c5cc01868d

Self-assembled sorbitol-derived supramolecular hydrogels for the controlled encapsulation and release of active pharmaceutical ingredients

Edward J. Howe, Babatunde O. Okesola, David K. Smith^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

A simple supramolecular hydrogel based on 1,3:2,4-di(4-acylhydrazide)benzylidene sorbitol (DBS-CONHNH<inf>2</inf>), is able to extract acid-functionalised anti-inflammatory drugs via directed interactions with the self-assembled gel nanofibres. Two-component hydrogel-drug hybrid materials can be easily formed by mixing and exhibit pH-controlled drug release. This journal is

Original language	English
Pages (from-to)	7451-7454
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	35
DOIs	https://doi.org/10.1039/c5cc01868d
Publication status	Published - 1 May 2015

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Howe_Smith_ChemComm2015
© Royal Society of Chemistry 2015. This is an author produced version of a paper published in Chemical Communications. Uploaded in accordance with the publisher's self-archiving policy.
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Self-assembled sorbitol-derived supramolecular hydrogels for the controlled encapsulation and release of active pharmaceutical ingredients

Abstract

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