Projects per year
Abstract
This paper reports the formation of silver (Ag) NPs within spatially-resolved two-component hydrogel beads that combine a low-molecular-weight gelator (LMWG) DBS-CONHNH2 and a polymer gelator (PG) calcium alginate. The AgNPs are formed via in situ reduction of Ag(I), with the resulting nanoparticle-loaded gels being characterised in detail. We tested the antibacterial activity of the nanocomposite gel beads against two drug-resistant bacterial strains, often associated with hospital-acquired infections: vancomycin-resistant Enterococcus faecium (VRE) and Pseudomonas aeruginosa (PA14), and the AgNP-loaded gels showed good antimicrobial properties against both types of bacteria. We suggest that the gel bead format of these AgNP-loaded hybrid hydrogels makes them promising versatile materials for potential applications in orthopaedics or wound healing.
Original language | English |
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Pages (from-to) | 8452-8457 |
Number of pages | 6 |
Journal | Chemistry : A European Journal |
Volume | 26 |
Early online date | 15 Apr 2020 |
DOIs | |
Publication status | E-pub ahead of print - 15 Apr 2020 |
Bibliographical note
© 2020 WILEY‐VCH Verlag GmbH & Co. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.Projects
- 2 Finished
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Multi-Domain Self-Assembled Gels: From Multi-Component Materials to Spatial and Temporal Control of Multi-component Biology
1/12/17 → 31/01/21
Project: Research project (funded) › Research
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GLYCOSENSE: Polymer brush sensing arrays for the identification of pathogens
1/02/17 → 23/10/19
Project: Research project (funded) › Research