Self-Assembling Supramolecular Hybrid Hydrogel Beads

TY - JOUR

T1 - Self-Assembling Supramolecular Hybrid Hydrogel Beads

AU - Piras, Carmen Cristina

AU - Slavik, Petr

AU - Smith, David Kelham

N1 - © 2019 The Authors.

PY - 2020/1/2

Y1 - 2020/1/2

N2 - With the goal of imposing shape and structure on supramolecular gels, we combine a low molecular weight gelator (LMWG) with the polymer gelator (PG) calcium alginate in a hybrid hydrogel. By imposing thermal and temporal control of the orthogonal gelation methods, the system either forms an extended inter-penetrating network or core-shell structured gel beads – a rare example of a supramolecular gel formulated inside discrete gel spheres. The self-assembled LMWG retains its unique properties within the beads, such as remediating Pd(II) and reducing it in situ to yield catalytically-active Pd(0) nanoparticles. A single PdNP-loaded gel bead can catalyse the Suzuki-Miyaura reaction, constituting a simple and easy-to-use reaction dosing form. These unique shaped and structured LMWG-filled gel beads are a versatile platform technology, with great potential in a range of applications.

AB - With the goal of imposing shape and structure on supramolecular gels, we combine a low molecular weight gelator (LMWG) with the polymer gelator (PG) calcium alginate in a hybrid hydrogel. By imposing thermal and temporal control of the orthogonal gelation methods, the system either forms an extended inter-penetrating network or core-shell structured gel beads – a rare example of a supramolecular gel formulated inside discrete gel spheres. The self-assembled LMWG retains its unique properties within the beads, such as remediating Pd(II) and reducing it in situ to yield catalytically-active Pd(0) nanoparticles. A single PdNP-loaded gel bead can catalyse the Suzuki-Miyaura reaction, constituting a simple and easy-to-use reaction dosing form. These unique shaped and structured LMWG-filled gel beads are a versatile platform technology, with great potential in a range of applications.

U2 - 10.1002/anie.201911404

DO - 10.1002/anie.201911404

M3 - Article

SN - 1433-7851

VL - 59

SP - 853

EP - 859

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

IS - 2

ER -