Self-organizing behaviour of glycosteroidal bolaphiles: Insights into lipidic microsegregation

R. Xu; F. Ali-Rachedi; N. M. Xavier; S. Chambert; F. Ferkous; Y. Queneau; S. J. Cowling; E. J. Davis; J. W. Goodby

doi:10.1039/c4ob02191f

Self-organizing behaviour of glycosteroidal bolaphiles: Insights into lipidic microsegregation

R. Xu, F. Ali-Rachedi, N. M. Xavier, S. Chambert, F. Ferkous, Y. Queneau^*, S. J. Cowling, E. J. Davis, J. W. Goodby

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

In this article we describe work on the synthesis of bolaphile biomimics composed of glucose head groups and steroidal units linked together by a methylene chain of varying length. The condensed phases formed by self-organization of the products as a function of temperature were characterized by differential scanning calorimetry and thermal polarized light microscopy. The results of these studies show that the thermal stabilities of the lamellar mesophases formed vary linearly as a function of increasing aliphatic composition, which reflects a linear hydrophobic-hydrophilic balance with respect to transition temperatures.

Original language	English
Pages (from-to)	783-792
Number of pages	10
Journal	Organic and Biomolecular Chemistry
Volume	13
Issue number	3
DOIs	https://doi.org/10.1039/c4ob02191f
Publication status	Published - 21 Jan 2015

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title = "Self-organizing behaviour of glycosteroidal bolaphiles: Insights into lipidic microsegregation",

abstract = "In this article we describe work on the synthesis of bolaphile biomimics composed of glucose head groups and steroidal units linked together by a methylene chain of varying length. The condensed phases formed by self-organization of the products as a function of temperature were characterized by differential scanning calorimetry and thermal polarized light microscopy. The results of these studies show that the thermal stabilities of the lamellar mesophases formed vary linearly as a function of increasing aliphatic composition, which reflects a linear hydrophobic-hydrophilic balance with respect to transition temperatures.",

author = "R. Xu and F. Ali-Rachedi and Xavier, {N. M.} and S. Chambert and F. Ferkous and Y. Queneau and Cowling, {S. J.} and Davis, {E. J.} and Goodby, {J. W.}",

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AU - Xu, R.

AU - Ali-Rachedi, F.

AU - Xavier, N. M.

AU - Chambert, S.

AU - Ferkous, F.

AU - Queneau, Y.

AU - Cowling, S. J.

AU - Davis, E. J.

AU - Goodby, J. W.

PY - 2015/1/21

Y1 - 2015/1/21

N2 - In this article we describe work on the synthesis of bolaphile biomimics composed of glucose head groups and steroidal units linked together by a methylene chain of varying length. The condensed phases formed by self-organization of the products as a function of temperature were characterized by differential scanning calorimetry and thermal polarized light microscopy. The results of these studies show that the thermal stabilities of the lamellar mesophases formed vary linearly as a function of increasing aliphatic composition, which reflects a linear hydrophobic-hydrophilic balance with respect to transition temperatures.

AB - In this article we describe work on the synthesis of bolaphile biomimics composed of glucose head groups and steroidal units linked together by a methylene chain of varying length. The condensed phases formed by self-organization of the products as a function of temperature were characterized by differential scanning calorimetry and thermal polarized light microscopy. The results of these studies show that the thermal stabilities of the lamellar mesophases formed vary linearly as a function of increasing aliphatic composition, which reflects a linear hydrophobic-hydrophilic balance with respect to transition temperatures.

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EP - 792

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 3

ER -

Self-organizing behaviour of glycosteroidal bolaphiles: Insights into lipidic microsegregation

Abstract

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