Serologic Evidence for Mother-to-Child Transmission of Kaposi Sarcoma–Associated Herpesvirus Infection

Dimitra Bourboulia, Denise Whitby, Chris Boshoff, Robert Newton, Valerie Beral, Henri Carrara, Anthony Lane, Freddy Sitas

Research output: Contribution to journalLetter

Abstract

To the Editor.— Kaposi sarcoma (KS)–associated herpesvirus (KSHV, or human herpesvirus 8 [HHV-8]) has been causally linked to KS. In the United Kingdom and the United States, sex between men may be an important route of transmission of HHV-8, because this is the main behavioral risk factor for KS in human immunodeficiency virus (HIV)–seropositive subjects. However, in parts of Africa where KS was seen in children even before the advent of the acquired immunodeficiency syndrome (AIDS), other routes of transmission also must occur.The Department of Human Genetics at the South African Institute of Medical Research in Johannesburg is responsible for testing mothers, children, and potential fathers in cases of disputed paternity. It is therefore possible to examine the relationship between seropositivity to HHV-8 in mothers and their children.
Original languageUndefined/Unknown
Pages (from-to)31-32
Number of pages2
JournalJAMA
Volume280
Issue number1
DOIs
Publication statusPublished - 1 Jul 1998

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