Shaping of calix[4]arenes via double bridging of the upper rim

Petr Slavík, Václav Eigner, Pavel Lhoták*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Direct double meta-mercuration can be used for subsequent bridging of a calix[4]arene skeleton via the installation of ketone moieties. This unprecedented substitution pattern in calixarene chemistry possesses a heavily distorted and rigid cavity capable of interactions with selected molecular guests as documented by binding of a CH2Cl2 molecule held in place by an intricate net of 10 specific (halogen bonding and hydrogen bonding) interactions from two neighbouring calixarene molecules.

Original languageEnglish
Pages (from-to)4964-4970
Number of pages7
Issue number26
Early online date1 Mar 2016
Publication statusPublished - 14 Jul 2016

Cite this